- Meeting abstract
- Open Access
Results after one year of rotavirus universal mass vaccination in Sicily
© Vitale et al. 2015
Published: 30 September 2015
Rotavirus (RV) vaccination is the best strategy to prevent hospitalizations due to rotavirus gastroenteritis (RVGE) and is strongly recommended by international health authority . The Sicilian Health Department introduced rotavirus universal mass vaccination (RUMV) into regional immunizations schedule in 2013 (mean vaccination coverage = 31%).
Intussusception is the invagination of one segment of the intestine within a more distal segment and even though the etiology is still unknown, in 1998, a relationship with a tetravalent rotavirus vaccine that was promptly withdrawn was suggested . Post licensure surveillance studies have not confirmed previous findings and no increased risk of intussusception was found between vaccinated infants with both of the actually licensed rotavirus vaccines [3, 4].
Aim of this study is to analyze the trend of RVGE hospitalizations and contextually to monitor the trend of intussusception in Sicily from 2009 to 2013 after one year of RUMV.
Material and methods
Were collected data from hospital discharge records occurred from 1st January 2009 to 31st December 2013 in Sicily.
Cases of RVGE were defined as all hospitalizations with an ICD-9-CM diagnosis code of 008.61 on any position . Furthermore, cases of intussusception were defined as all hospitalizations with an ICD-9-CM code of 560.0 on any discharge diagnoses.
After one year of surveillance and despite reaching low vaccination coverage, our results demonstrated the high effectiveness of the RUMV strategy on reduction of RV circulation. Similar data on RV vaccination efficacy on early vaccination campaign was reported in Belgium .
Moreover, the steadiness of intussusception hospitalizations after introduction of RV vaccination allows us to confirm the security profile of the available vaccine.
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