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Table 1 Clinical and biochemical characteristics of CPP cases diagnosed before and after lockdown measures

From: Central precocious puberty during COVID-19 pandemic and sleep disturbance: an exploratory study

 

CPP before lockdown

(N = 34)

CPP during lockdown

(N = 35)

P

Age (ys)

7.97 ± 1.11

7.59 ± 0.67

0.10

Height (cm)

129.25 ± 6.99

129.69 ± 5.87

0.66

DS-Height

0.17 ± 1.04

0.78 ± 1.0

0.05

Z-score BMI

0.60 ± 0.66

0.23 ± 1.51

0.31

Bone age (ys)

9.33 ± 1.12

8.77 ± 0.67

0.19

LH (UI/ml)

0.87 ± 0.79

1.23 ± 1.12

0.03

FSH (UI/ml)

4.34 ± 2.43

7.09 ± 2.47

0.02

Peak LH (UI/ml)

8.93 ± 4.35

8.05 ± 2.47

0.60

17-beta estradiol (pg/ml)

19.38 ± 14.23

30.88 ± 22.53

0.04

Positive familial history (%)

21.4

46.4

0.18

  1. BMI body mass index, FSH follicle-stimulating hormone, LH Luteinizing hormone
  2. Data are expressed as mean ± standard deviations or as frequencies