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Table 1 Clinical and biochemical characteristics of CPP cases diagnosed before and after lockdown measures

From: Central precocious puberty during COVID-19 pandemic and sleep disturbance: an exploratory study

  CPP before lockdown
(N = 34)
CPP during lockdown
(N = 35)
P
Age (ys) 7.97 ± 1.11 7.59 ± 0.67 0.10
Height (cm) 129.25 ± 6.99 129.69 ± 5.87 0.66
DS-Height 0.17 ± 1.04 0.78 ± 1.0 0.05
Z-score BMI 0.60 ± 0.66 0.23 ± 1.51 0.31
Bone age (ys) 9.33 ± 1.12 8.77 ± 0.67 0.19
LH (UI/ml) 0.87 ± 0.79 1.23 ± 1.12 0.03
FSH (UI/ml) 4.34 ± 2.43 7.09 ± 2.47 0.02
Peak LH (UI/ml) 8.93 ± 4.35 8.05 ± 2.47 0.60
17-beta estradiol (pg/ml) 19.38 ± 14.23 30.88 ± 22.53 0.04
Positive familial history (%) 21.4 46.4 0.18
  1. BMI body mass index, FSH follicle-stimulating hormone, LH Luteinizing hormone
  2. Data are expressed as mean ± standard deviations or as frequencies