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  1. We proposed to analyze thoroughly the impact of the COVID-19 lockdown (CL) in changes of profiles and in trend of the domestic accidents (DAs) in children.

    Authors: Valentina Ferro, Raffaella Nacca, Mara Pisani, Sebastian Cristaldi, Maria Francesca Faa, Maria Chiara Supino, Umberto Raucci, Antonino Reale, Marta Ciofi Degli Atti, Massimiliano Raponi, Alberto Villani and Anna Maria Musolino
    Citation: Italian Journal of Pediatrics 2022 48:129
  2. Quarantine and isolation measures during COVID-19 pandemic may have caused additional stress and challenged the mental health of the youth. Aim of the study is to investigate the COVID-19 pandemic impact on ne...

    Authors: Elena Bozzola, Pietro Ferrara, Giulia Spina, Alberto Villani, Marco Roversi, Massimiliano Raponi, Giovanni Corsello and Annamaria Staiano
    Citation: Italian Journal of Pediatrics 2022 48:126
  3. Neurological vertigo is a common symptom in children and adults presenting to the emergency department (ED) and its evaluation may be challenging, requiring often the intervention of different medical specialt...

    Authors: Noemi Pellegrino, Vincenzo Di Stefano, Eleonora Rotondo, Alessandro Graziosi, Marianna Gabriella Rispoli, Angelo Torrente, Antonino Lupica, Filippo Brighina, Umberto Raucci and Pasquale Parisi
    Citation: Italian Journal of Pediatrics 2022 48:125
  4. Ventricular septal defects (VSDs) are one of the leading causes of death due to cardiac anomalies during the first months of life. The prevalence of VSD in neonates is reported up to 4%. Despite the remarkable...

    Authors: Sumbal Sarwar, Shabana, Amna Tahir, Zainab Liaqat, Saher Naseer, Rani Summeya Seme, Sabahat Mehmood, Saleem Ullah Shahid and Shahida Hasnain
    Citation: Italian Journal of Pediatrics 2022 48:124
  5. Albright’s hereditary osteodystrophy (AHO) is an inherited disorder which is caused by an inactivating variant in the GNAS gene. AHO appears associated to either pseudohypoparathyroidism 1a (PHP1a) when GNAS gene...

    Authors: Qing Zhou, Bin Liang, Qing-Xian Fu, Hui Liu and Chao-Chun Zou
    Citation: Italian Journal of Pediatrics 2022 48:123
  6. With the increasing incidence of asymptomatic carriers or milder symptoms, children and adolescents are likely to become a silent source of infection. In view of the efficacy and safety of vaccines in the trea...

    Authors: Lin Wang, Wen Wen, Chen Chen, Jiake Tang, Chunyi Wang, Mengyun Zhou, Yongran Cheng, Xingwei Zhang, Mingwei Wang, Zhanhui Feng and Weiqian Wang
    Citation: Italian Journal of Pediatrics 2022 48:122
  7. Prader-Willi syndrome (PWS) is a complex disorder caused by impaired paternally expressed genes on chromosome 15q11-q13. Variable findings have been reported about the phenotypic differences among PWS genetic ...

    Authors: Lu Zhang, Xiaoliang Liu, Yunjing Zhao, Qingyi Wang, Yuanyuan Zhang, Haiming Gao, Bijun Zhang, Wanting Cui and Yanyan Zhao
    Citation: Italian Journal of Pediatrics 2022 48:121
  8. The bacterial load of the human lower respiratory tract is at least several times lower than that of the other parts of the body. This study aimed to identify the bacterial composition and colony structure of ...

    Authors: Jiawei Yao, Tao Ai, Wanmin Xia, Yinghong Fan, Cheng Xie and Lei Zhang
    Citation: Italian Journal of Pediatrics 2022 48:120
  9. E-cigarettes are devices which allow to aerosolize liquids containing nicotine or other substances. Ever since they were released on the market in 2006, the number of users have been constantly increasing, esp...

    Authors: Chiara Casamento Tumeo, Alessandra Schiavino, Maria Giovanna Paglietti, Francesca Petreschi, Alessandra Ottavianelli, Alessandro Onofri, Claudio Cherchi, Paolo Tomà and Renato Cutrera
    Citation: Italian Journal of Pediatrics 2022 48:119
  10. The rate of chronic drooling in children older than 4 years is 0.5%, but it rises to 60% in those with neurological disorders. Physical and psychosocial consequences lead to a reduction in the quality of Life ...

    Authors: Antonella Riva, Elisabetta Amadori, Maria Stella Vari, Alberto Spalice, Vincenzo Belcastro, Maurizio Viri, Donatella Capodiferro, Antonino Romeo, Alberto Verrotti and Pasquale Striano
    Citation: Italian Journal of Pediatrics 2022 48:118
  11. Preterm extremely low birth weight infants (ELBWi) are known to be at greater risk of developing neuropsychiatric diseases. Identifying early predictors of outcome is essential to refer patients for early inte...

    Authors: Camilla Caporali, Stefania Longo, Giovanna Tritto, Gianfranco Perotti, Camilla Pisoni, Cecilia Naboni, Barbara Gardella, Arsenio Spinillo, Federica Manzoni, Stefano Ghirardello, Renato Borgatti and Simona Orcesi
    Citation: Italian Journal of Pediatrics 2022 48:117
  12. Hypokalemic periodic paralysis is a rare neuromuscular genetic disorder due to defect of ion channels and subsequent function impairment. It belongs to a periodic paralyses group including hyperkalemic periodi...

    Authors: Maria Carolina Colucci, Marica Fabiana Triolo, Simona Petrucci, Flaminia Pugnaloni, Massimiliano Corsino, Melania Evangelisti, Maria Cecilia D’Asdia, Giovanni Di Nardo, Matteo Garibaldi, Gianluca Terrin and Pasquale Parisi
    Citation: Italian Journal of Pediatrics 2022 48:116
  13. It is now well established that atherosclerosis begins in childhood and evolves through adolescence and young adulthood, ultimately resulting in myocardial infarction and stroke in adults.

    Authors: Giuseppe Banderali, Maria Elena Capra, Giacomo Biasucci, Rita Stracquadaino, Claudia Viggiano and Cristina Pederiva
    Citation: Italian Journal of Pediatrics 2022 48:115
  14. Despite simple and proven cost-effective measures were available to prevent birth asphyxia; studies suggested that there has been limited progress in preventing birth asphyxia even in healthy full-term neonate...

    Authors: Masresha Asmare Techane, Tewodros Getaneh Alemu, Chalachew Adugna Wubneh, Getaneh Mulualem Belay, Tadesse Tarik Tamir, Addis Bilal Muhye, Destaye Guadie Kassie, Amare Wondim, Bewuketu Terefe, Bethelihem Tigabu Tarekegn, Mohammed Seid Ali, Beletech Fentie, Almaz Tefera Gonete, Berhan Tekeba, Selam Fisiha Kassa, Bogale Kassahun Desta…
    Citation: Italian Journal of Pediatrics 2022 48:114
  15. Studies published on gender-related differences in the gambling behavior of adolescents have focused mainly on psychological and social factors. The aim of this study was to develop separate risk factor models...

    Authors: Alessandra Buja, Milena Sperotto, Bruno Genetti, Paolo Vian, Fabio Vittadello, Elisabetta Simeoni, Chiara Zampieri and Vincenzo Baldo
    Citation: Italian Journal of Pediatrics 2022 48:113
  16. Autism spectrum disorder (ASD) is one of the serious developmental disorders that is usually diagnosed below the age of three years. Although the severity of the disease’s symptoms varies from patient to patie...

    Authors: Nader Salari, Shabnam Rasoulpoor, Shna Rasoulpoor, Shamarina Shohaimi, Sima Jafarpour, Nasrin Abdoli, Behnam Khaledi-Paveh and Masoud Mohammadi
    Citation: Italian Journal of Pediatrics 2022 48:112
  17. Cathelicidin/LL-37 plays a significant role in the human immune defense reaction. Preterm human immature organs being exposed to inflammation-induced injury was the critical denominator leading to the common p...

    Authors: Zhuxiao Ren, Wenhui Mo, Liling Yang, Jianlan Wang, Qi Zhang, Zhicheng Zhong, Wei Wei, Zhipeng Liu, Zhiping Wu, Yao Yao and Jie Yang
    Citation: Italian Journal of Pediatrics 2022 48:111
  18. Available guidelines for asthma management represent an important and suitable tool to make the entire medical process evidence-based, effective, and safe for patients. Their purpose is to help doctors and pat...

    Authors: Elio Novembre, Mattia Giovannini, Simona Barni and Francesca Mori
    Citation: Italian Journal of Pediatrics 2022 48:110
  19. The potential use of biomarkers in the diagnosis of fungal infections is a challenge. The aim of this study was to evaluate the role of a biomarker-guided antifungal stewardship program for hospitalized pediat...

    Authors: Parisa Badiee, Ali Amanati, Fatemeh Ghasemi and Hadis Jafarian
    Citation: Italian Journal of Pediatrics 2022 48:109
  20. Adolescence is characterized by emotional instability and risk-taking behaviours that can lead to, among other things, an increased risk of developing pathological video-gaming and gambling habits. The aim of ...

    Authors: Loredana Cena, Matteo Rota, Stefano Calza, Alice Trainini, Sara Zecca, Sofia Bonetti Zappa, Luisa Silvia Nodari and Alberto Stefana
    Citation: Italian Journal of Pediatrics 2022 48:108
  21. Myogenic Arthrogryposis Multiplex Congenita type 3 (AMC-3), is a rare congenital condition characterized by severe hypotonia, club feet, and multiple joint contractures often affecting both arms and legs which...

    Authors: Naglaa M. Kamal, AlaaEddin M. Alzeky, Maher R. Omair, Ruwayd A. Attar, Abdullah M. Alotaibi, Abdullah Safar, Nawal S. Alosaimi and Sara A. S. Abosabie
    Citation: Italian Journal of Pediatrics 2022 48:107
  22. The assessment of body composition is central in diagnosis and treatment of paediatric obesity, but a criterion method is not feasible in clinical practice. Even the use of bioelectrical impedance analysis (BI...

    Authors: Maria Rosaria Licenziati, Giada Ballarin, Gabriella Iannuzzo, Maria Serena Lonardo, Olivia Di Vincenzo, Arcangelo Iannuzzi and Giuliana Valerio
    Citation: Italian Journal of Pediatrics 2022 48:106
  23. Beta thalassemia major (β-TM) is a common cause of skeletal morbidity and is associated with increased bone fracture risk, particularly in inadequately transfused children. The aim of this study was to investi...

    Authors: Tanju Çelik, Özlem Sangün, Şule Ünal, Ali Balcı and Sedat Motor
    Citation: Italian Journal of Pediatrics 2022 48:105
  24. To investigate the coping strategies of a group of adolescents with somatic symptom disorder compared to non-somatic symptom disorder peers during the COVID-19 related lockdown.

    Authors: Andrea Trombetta, Laura De Nardi, Giorgio Cozzi, Luca Ronfani, Lara Bigolin, Egidio Barbi, Matteo Bramuzzo and Giuseppe Abbracciavento
    Citation: Italian Journal of Pediatrics 2022 48:104
  25. Phototherapy (PT) is the most often utilized technique for treating and preventing severe hyperbilirubinemia in the term and preterm newborns. PT's proven benefit is that it decreases the requirement for excha...

    Authors: Mai Rabie El-Sheikh, Amira Youssef Ahmed, Abd EL-Rahman Mohamed ELMashad, Ibrahim Ibrahim Talaye and Eslam El-Sayed El-Hawary
    Citation: Italian Journal of Pediatrics 2022 48:103
  26. Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Although many reports have detailed a range of neurological symptoms in SARS-C...

    Authors: Martina Capponi, Bianca Laura Cinicola, Giulia Brindisi, Cristiana Alessia Guido, Maria Cristina Torcé, Anna Maria Zicari and Alberto Spalice
    Citation: Italian Journal of Pediatrics 2022 48:102
  27. Multiple gestations represent a considerable proportion of pregnancies delivering in the late preterm (LP) period. Only 30% of LP twins are due to spontaneous preterm labor and 70% are medically indicated; amo...

    Authors: Francesca Monari, Giuseppe Chiossi, Michela Ballarini, Daniela Menichini, Giancarlo Gargano, Alessandra Coscia, Dante Baronciani and Fabio Facchinetti
    Citation: Italian Journal of Pediatrics 2022 48:101
  28. In our third-level Neonatal Unit in Northern Italy, we recorded a high rate of neonatal hyperbilirubinemia requiring phototherapy in March-November 2020, during the first phase of COVID-19 pandemic, compared t...

    Authors: Alice Monzani, Valentino Remorgida and Ivana Rabbone
    Citation: Italian Journal of Pediatrics 2022 48:100
  29. Brain abscesses are uncommon but life-threatening in extremely preterm (EP, Gestational Age < 28 weeks) infants. The information of long-time follow-up is rare, but very few cases presented almost intact neura...

    Authors: Shulin Pan, Su Lin, Jing Lin, Shangqin Chen and Zhenlang Lin
    Citation: Italian Journal of Pediatrics 2022 48:99
  30. The use of electronic cigarettes (e-cigarette) and vaping devices started as a potential aid for cessation and reducing the harmful consequences of cigarette smoking, mainly in the adult population. Today e-ci...

    Authors: Fabrizio Virgili, Raffaella Nenna, Shira Ben David, Enrica Mancino, Greta Di Mattia, Luigi Matera, Laura Petrarca and Fabio Midulla
    Citation: Italian Journal of Pediatrics 2022 48:97
  31. Although Anorexia Nervosa (AN) patients show dysfunctional behaviour in information processing, visual and verbal memory performance, and different cognitive fields, regardless of their BMI, the literature on ...

    Authors: Salvatore Ferdinando Aruta, Jacopo Pruccoli, Nicole Bandini, Paola Rucci and Antonia Parmeggiani
    Citation: Italian Journal of Pediatrics 2022 48:96
  32. Currently, there are a few detailed guidelines on the overall management of children and adolescents with moderate-severe atopic dermatitis. AD ​​is a complex disease presenting with different clinical phenoty...

    Authors: Elena Galli, Anna Belloni Fortina, Giampaolo Ricci, Nunzia Maiello, Iria Neri, Ermanno Baldo, Irene Berti, Domenico Bonamonte, Lucetta Capra, Elena Carboni, Rossella Carello, Francesca Caroppo, Giovanni Cavagni, Iolanda Chinellato, Francesca Cipriani, Pasquale Comberiati…
    Citation: Italian Journal of Pediatrics 2022 48:95
  33. Autoimmune encephalitis (AE) is a type of encephalopathy mediated by an antigenic immune response in the central nervous system. Most research related to autoimmune encephalitis (AE) is focused on early diagno...

    Authors: Jin-Yue Huang, Wen-Xuan Fan, Jing Meng, Chun-Quan Cai and Dong Li
    Citation: Italian Journal of Pediatrics 2022 48:94
  34. COVID toes or chilblain-like skin lesions have been widely reported during COVID-19 pandemic. Most cases were described in patients with negative microbiological tests for SARS-CoV-2, therefore the possible re...

    Authors: Roberto Paparella, Luigi Tarani, Enrico Properzi, Francesco Costantino, Chiara Saburri, Roberta Lucibello, Antonio Richetta, Alberto Spalice and Lucia Leonardi
    Citation: Italian Journal of Pediatrics 2022 48:93
  35. Evidence suggests that many parents who care for their children with cancer are affected by the care burden due to the chronic nature of the disease. The aim of this study was to determine the burden of care l...

    Authors: Mahnaz Chaghazardi, Maryam Janatolmakan, Shahab Rezaeian and Alireza Khatony
    Citation: Italian Journal of Pediatrics 2022 48:92
  36. In this study, we used the novel DeepGestalt technology powered by Face2Gene (FDNA Inc., MA, USA) in suggesting a correct diagnosis based on the facial gestalt of well-known multiple anomaly syndromes. Only mo...

    Authors: Giulia Pascolini, Mauro Calvani and Paola Grammatico
    Citation: Italian Journal of Pediatrics 2022 48:91
  37. Intercepting earlier suspected TB (Tuberculosis) cases clinically is necessary to reduce TB incidence, so we described signs and symptoms of retrospective cases of pulmonary TB and tried to evaluate which coul...

    Authors: Elisa Farina, Carmen D’Amore, Laura Lancella, Elena Boccuzzi, Marta Luisa Ciofi degli Atti, Antonino Reale, Paolo Rossi, Alberto Villani, Massimiliano Raponi and Umberto Raucci
    Citation: Italian Journal of Pediatrics 2022 48:90
  38. The Congenital Adrenal Hyperplasia due to 21 hydroxylase deficiency is the most common cause of genital ambiguity in persons with XX sexual chromosomes. Genital ambiguity among persons with XY sexual chromosom...

    Authors: Reinaldo Luna de Omena Filho, Reginaldo José Petroli, Fernanda Caroline Soardi, Débora de Paula Michelatto, Taís Nitsch Mazzola, Helena Fabbri-Scallet, Maricilda Palandi de Mello, Susane Vasconcelos Zanotti, Ida Cristina Gubert and Isabella Monlleo
    Citation: Italian Journal of Pediatrics 2022 48:89
  39. COVID-19 lockdown caused sudden changes in people’s lifestyle, as a consequence of the forced lockdown imposed by governments all over the world. We aimed to evaluate the impact of lockdown on body mass index ...

    Authors: Giulia Brindisi, Vincenza Patrizia Di Marino, Francesca Olivero, Daniela De Canditiis, Giovanna De Castro, Anna Maria Zicari and Caterina Anania
    Citation: Italian Journal of Pediatrics 2022 48:88
  40. Epidemiologic data suggest an increased prevalence of pediatric food allergies and intolerances (FAIs) during the last decades. This changing scenario has led to an increase in the overall healthcare costs, du...

    Authors: Roberto Berni Canani, Carlo Caffarelli, Mauro Calvani, Alberto Martelli, Laura Carucci, Tommaso Cozzolino, Patrizia Alvisi, Carlo Agostoni, Paolo Lionetti and Gian Luigi Marseglia
    Citation: Italian Journal of Pediatrics 2022 48:87
  41. Children’s HIV-positive status disclosure is an essential component of chronic care & long-term disease management. The modalities of status disclosure are complex and vary across different communities. Althou...

    Authors: Belete Gelaw Walle, Chalie Marew Tiruneh, Tigabu Dessie, Nigusie Selomon, Amare Kassaw, Bogale Chekole, Moges Wubneh, Tadele Lankrew and Wubet Alebachew Bayih
    Citation: Italian Journal of Pediatrics 2022 48:86
  42. Loeys-Dietz syndrome (LDS) is a rare connective tissue disorder characterized by cardiovascular manifestations, especially aortic dilatations and arterial tortuosity, craniofacial and skeletal features, joint ...

    Authors: Francesco Baldo, Laura Morra, Agnese Feresin, Flavio Faletra, Yasmin Al Naber, Luigi Memo and Laura Travan
    Citation: Italian Journal of Pediatrics 2022 48:85
  43. Limping and/or refusal to walk is a common complaint in the setting of the pediatric department, with a widely diverse differential diagnosis. An unusual etiology, is that of a hereditary neuropathy.

    Authors: Shani Karklinsky, Shir Kugler, Omer Bar-Yosef, Andreea Nissenkorn, Anat Grossman-Jonish, Irit Tirosh, Asaf Vivante and Ben Pode-Shakked
    Citation: Italian Journal of Pediatrics 2022 48:84
  44. Long COVID-19 syndrome is a complex of symptoms that occurs after the acute SARS-CoV-2 infection, in the absence of other possible diagnoses. Studies on Long COVID-19 in pediatric population are scanty and het...

    Authors: Gianfranco Trapani, Giuseppe Verlato, Enrico Bertino, Giulia Maiocco, Roberta Vesentini, Alessia Spadavecchia, Angelica Dessì and Vassilios Fanos
    Citation: Italian Journal of Pediatrics 2022 48:83
  45. Ophthalmoplegic migraine, renamed "Recurrent Painful Ophthalmoplegic Neuropathy" (RPON) in 2013 by the International Headache Society is a rare neurologic disorder characterized by recurrent attacks of ophthalmop...

    Authors: Raffaele Falsaperla, Santiago Presti, Manuela Lo Bianco, Stefano Catanzaro, Silvia Marino and Martino Ruggieri
    Citation: Italian Journal of Pediatrics 2022 48:82
  46. Providing appropriate care at birth remains a crucial strategy for reducing neonatal mortality and morbidity. We aimed to evaluate the consistency of practice and the adherence to the international guidelines ...

    Authors: Camilla Gizzi, Daniele Trevisanuto, Luigi Gagliardi, Giulia Vertecchi, Stefano Ghirardello, Sandra Di Fabio, Corrado Moretti and Fabio Mosca
    Citation: Italian Journal of Pediatrics 2022 48:81
  47. S100B is an established biomarker of brain development and damage. Lutein (LT) is a naturally occurring xanthophyll carotenoid mainly concentrated in the central nervous system (CNS), but its neurotrophic role...

    Authors: Simonetta Picone, Alberto Ritieni, Giulia Graziani, Piermichele Paolillo, Ebe D’Adamo, Valentina Botondi, Daniele Panichi, Sara Torresi, Daniela David, Armando di Ludovico, Francesco Chiarelli and Diego Gazzolo
    Citation: Italian Journal of Pediatrics 2022 48:80
  48. SARS-CoV-2 infection in the pediatric age group has a milder course than in adults, but in some cases even children may present with severe forms or develop long-term consequences. The aim of this study was to...

    Authors: Silvia Bloise, Sara Isoldi, Alessia Marcellino, Enrica De Luca, Anna Dilillo, Saverio Mallardo, Vanessa Martucci, Mariateresa Sanseviero, Emanuela Del Giudice, Donatella Iorfida, Rita Leone, Alessia Testa, Beatrice Frasacco, Pietro Gizzone, Claudia Proietti Ciolli, Alessandro Sinceri…
    Citation: Italian Journal of Pediatrics 2022 48:79

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