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  1. Osteochondroma generally occurs as a single lesion and it is not a heritable disease. When two or more osteochondroma are present, this condition represents a genetic disorder named hereditary multiple exostos...

    Authors: Mauro Bozzola, Chiara Gertosio, Maria Gnoli, Federico Baronio, Elena Pedrini, Cristina Meazza and Luca Sangiorgi
    Citation: Italian Journal of Pediatrics 2015 41:53
  2. Intussusception is the most common cause of bowel obstruction in infants with an incidence ranging from 9–328 cases per 100,000 infants aged 0–11 months. Causes underlining this clinical manifestation are stil...

    Authors: Claudio Costantino, Vincenzo Restivo, Mario Cuccia, Roberto Furnari, Emanuele Amodio and Francesco Vitale
    Citation: Italian Journal of Pediatrics 2015 41:52
  3. Several factors can interfere with the full physical and emotional growth of adolescents, among them chronic diseases. The aim was to determine the nutritional status of adolescents and to associate it with pu...

    Authors: Ieda Regina Lopes Del Ciampo, Luiz Antonio Del Ciampo, Regina Sawamura, Laiane Renolfi de Oliveira and Maria Inez Machado Fernandes
    Citation: Italian Journal of Pediatrics 2015 41:51
  4. Sex chromosomal aneuploidies in males are rare diseases with an overwhelming involvement of endocrinological and auxological issues; less frequently, other anomalies are observed. Neuroradiological issues are ...

    Authors: Donatella Milani, Francesca Bonarrigo, Sabrina Avignone, Fabio Triulzi and Susanna Esposito
    Citation: Italian Journal of Pediatrics 2015 41:50
  5. Intravenous fluids are commonly prescribed in childhood. 0.9 % saline is the most-used fluid in pediatrics as resuscitation or maintenance solution. Experimental studies and observations in adults suggest that...

    Authors: Maristella Santi, Sebastiano A. G. Lava, Pietro Camozzi, Olivier Giannini, Gregorio P. Milani, Giacomo D. Simonetti, Emilio F. Fossali, Mario G. Bianchetti and Pietro B. Faré
    Citation: Italian Journal of Pediatrics 2015 41:47
  6. Dent disease is a rare X-linked tubulopathy with low molecular weight proteinuria, hypercalciuria, nephrolithiasis, nephrocalcinosis and progressive renal failure. We describe the case of a 9-year-old boy who ...

    Authors: Chiara De Mutiis, Andrea Pasini, Claudio La Scola, Fabrizio Pugliese and Giovanni Montini
    Citation: Italian Journal of Pediatrics 2015 41:46
  7. A highly variable phenotype characterized by thyroid, respiratory and neurological defects has been reported in an already established group of disorders namely NKX2.1-related disorders. We describe here the case...

    Authors: Sara Monti, Annalisa Nicoletti, Antonella Cantasano, Heiko Krude and Alessandra Cassio
    Citation: Italian Journal of Pediatrics 2015 41:45
  8. Infections are common complications occurring in malnourished childrenas a result of impaired immunity. Urinary tract infections (UTI) have been found to be the commonest cause of fever in normal children in d...

    Authors: Maimuna Ahmed, Nyambura Moremi, Mariam M. Mirambo, Adolfine Hokororo, Martha F. Mushi, Jeremiah Seni, Erasmus Kamugisha and Stephen E. Mshana
    Citation: Italian Journal of Pediatrics 2015 41:44
  9. Bloodstream infection (BSI) is one of the most common causes of nosocomial infection in neonatal intensive care units (NICU). The aim of the present study was to determine bacterial agents and their susceptibi...

    Authors: Bahram Nikkhoo, Fariba Lahurpur, Ali Delpisheh, Mohammad Aziz Rasouli and Abdorrahim Afkhamzadeh
    Citation: Italian Journal of Pediatrics 2015 41:43
  10. Both extensively hydrolysed formulas (eHF) and amino acid-based formula (AAFs) have been demonstrated effective for the treatment of CMA. However, in clinical practice, parents complain that hydrolysates are r...

    Authors: Michele Miraglia Del Giudice, Enza D’Auria, Diego Peroni, Samuele Palazzo, Giovanni Radaelli, Pasquale Comberiati, Francesca Galdo, Nunzia Maiello and Enrica Riva
    Citation: Italian Journal of Pediatrics 2015 41:42
  11. Respiratory Syncytial Virus (RSV) is one of the main causes of respiratory infections during the first year of life. Very premature infants may contract more severe diseases and ‘late preterm infants’ may also...

    Authors: Marcello Lanari, Federica Prinelli, Fulvio Adorni, Simona Di Santo, Silvia Vandini, Michela Silvestri and Massimo Musicco
    Citation: Italian Journal of Pediatrics 2015 41:40
  12. Aim of this commentary is to summarize the salient literature news on the relationships between autoimmune thyroid diseases (ATDs) and either Down syndrome (DS) or Turner syndrome (TS).

    Authors: Tommaso Aversa, Fortunato Lombardo, Mariella Valenzise, Maria Francesca Messina, Concetta Sferlazzas, Giuseppina Salzano, Filippo De Luca and Malgorzata Wasniewska
    Citation: Italian Journal of Pediatrics 2015 41:39
  13. Fanconi anemia (FA) is a genetically heterogeneous rare autosomal recessive disorder characterized by congenital malformations, hematological problems and predisposition to malignancies. The genes that have be...

    Authors: Ponnumony John Solomon, Priya Margaret, Ramya Rajendran, Revathy Ramalingam, Godfred A Menezes, Alph S Shirley, Seung Jun Lee, Moon-Woo Seong, Sung Sup Park, Dodam Seol and Soo Hyun Seo
    Citation: Italian Journal of Pediatrics 2015 41:38
  14. Acute otitis media (AOM) is one of the most common childhood infectious diseases. The recent Italian Pediatric Guidelines for the treatment of AOM constitutes a step forward in the management of children with ...

    Authors: Silvia Palma, Cristiano Rosafio, Cinzia Del Giovane, Viviana Dora Patianna, Laura Lucaccioni, Elisabetta Genovese, Paolo Bertolani and Lorenzo Iughetti
    Citation: Italian Journal of Pediatrics 2015 41:37
  15. Weaning (or introduction of complementary feeding) is a special and important moment in the growth of a child, both for the family and the infant itself, and it can play a major role in the child’s future heal...

    Authors: Patrizia Alvisi, Sandra Brusa, Stefano Alboresi, Sergio Amarri, Paolo Bottau, Giovanni Cavagni, Barbara Corradini, Linda Landi, Leonardo Loroni, Miris Marani, Irene M Osti, Carlotta Povesi-Dascola, Carlo Caffarelli, Luca Valeriani and Carlo Agostoni
    Citation: Italian Journal of Pediatrics 2015 41:36
  16. To retrospectively identify the individual risk factors for the urethrocutaneous fistula (UCF) in pediatric patients after hypospadias repair (HR) with onlay island flap urethroplasty.

    Authors: Li-Qu Huang, Zheng Ge, Jun Tian, Geng Ma, Ru-Gang Lu, Yong-Ji Deng, Li-Xia Wang, Chen-Jun Chen, Hao-Bo Zhu, Xiao-Jiang Zhu and Yun-Fei Guo
    Citation: Italian Journal of Pediatrics 2015 41:35
  17. Nutritional habits are a useful way to characterize whole diets and they are also known to be influenced by a wide range of social and economic factors. The above factors in each country may have different eff...

    Authors: Aušra Petrauskienė, Vilma Žaltauskė and Edita Albavičiūtė
    Citation: Italian Journal of Pediatrics 2015 41:34
  18. Acute respiratory infections (ARIs) cause illness. Children under five years of age are highly vulnerable to these infections. Viral coinfection or multiple viral infection is a variable that can have a signif...

    Authors: Jahaziel Diaz, Jaime Morales-Romero, Gustavo Pérez-Gil, Martín Bedolla-Barajas, Netzahualpilli Delgado-Figueroa, Rebeca García-Román, Omar López-López, Evelyn Bañuelos, Cristal Rizada-Antel, Roberto Zenteno-Cuevas, Ángel Ramos-Ligonio, Clara Luz Sampieri, Luis Gustavo Orozco-Alatorre, Silvia I Mora and Hilda Montero
    Citation: Italian Journal of Pediatrics 2015 41:33
  19. The diagnosis of epilepsy should be made as early as possible to give a child the best chance for treatment success and also to decrease complications such as learning difficulties and social and behavioral pr...

    Authors: Seham FA Azab, Laila M Sherief, Safaa H Saleh, Mona M Elshafeiy, Ahmed G Siam, Wafaa F Elsaeed, Mohamed A Arafa, Eman A Bendary, Hanan S Sherbiny, Rabab M Elbehedy and Khalid A Aziz
    Citation: Italian Journal of Pediatrics 2015 41:32
  20. HOXA genes cluster plays a fundamental role in embryologic development. Deletion of the entire cluster is known to cause a clinically recognizable syndrome with mild developmental delay, characteristic facies,...

    Authors: Lidia Pezzani, Donatella Milani, Francesca Manzoni, Marco Baccarin, Rosamaria Silipigni, Silvana Guerneri and Susanna Esposito
    Citation: Italian Journal of Pediatrics 2015 41:31
  21. It is of high incidence of brain injuries in premature infants, so it is necessary to diagnose and treat the brain injury early for neonatal clinical practice. We are aimed to investigate the relationship betw...

    Authors: Yang Duan, Fu-qiang Sun, Yue-qin Li, Sheng-shun Que, Su-yan Yang, Wen-jing Xu, Wen-hong Yu, Jun-hua Chen, Ya-jie Lu and Xin Li
    Citation: Italian Journal of Pediatrics 2015 41:30
  22. The main modifiable risk factors for obesity are related to lifestyle and significantly influenced by the family, environment and culture. We aimed to estimate the prevalence of overweight/obesity and associat...

    Authors: Renata Geremia, Hosana Maria Speranza Cimadon, William Brasil de Souza and Lucia Campos Pellanda
    Citation: Italian Journal of Pediatrics 2015 41:28
  23. Severe infections represent the main cause of neonatal mortality accounting for more than one million neonatal deaths worldwide every year. Antibiotics are the most commonly prescribed medications in neonatal ...

    Authors: Chryssoula Tzialla, Alessandro Borghesi, Gregorio Serra, Mauro Stronati and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2015 41:27
  24. Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection. Here, we repo...

    Authors: Fabio Natale, Bianca Bizzarri, Veronica Cardi, Aurelia Gaeta, Paola Villani, Giuseppina Liuzzi and Mario De Curtis
    Citation: Italian Journal of Pediatrics 2015 41:26
  25. We compared the efficacy of and consistency in manual ventilation by trained healthcare professionals using three devices: self-inflating bag, flow-inflating bag, and T-piece resuscitator.

    Authors: Somashekhar M Nimbalkar, Suman Rao PN, Saudamini V Nesargi, Ashish R Dongara and Swarnarekha Bhat
    Citation: Italian Journal of Pediatrics 2015 41:25
  26. Using data from the Hospital Discharge data-base (SDO) and from the Certificate of Delivery Assistance data-base (CedAP) we analysed mode of delivery and neonatal care in public and private hospitals in Lombar...

    Authors: Fabio Parazzini, Sonia Cipriani, Giuseppe Bulfoni, Camilla Bulfoni, Roberto Bellù, Rinaldo Zanini and Fabio Mosca
    Citation: Italian Journal of Pediatrics 2015 41:24
  27. Ataxia-Telangiectasia is a rare multisystem autosomal recessive disorder [OMIM 208900], caused by mutations in Ataxia-Telangiectasia Mutated gene. It is characterized by neurological, immunological and cutaneo...

    Authors: Nicoletta Cantarutti, Alessia Claps, Giulia Angelino, Luciana Chessa, Francesco Callea, May El Hachem, Andrea Diociaiuti and Andrea Finocchi
    Citation: Italian Journal of Pediatrics 2015 41:23
  28. Thoracic outlet syndrome (TOS) is largely overlooked in children and adolescents because the condition is not widely viewed as a pediatric disorder. This study aimed to clarify the causes, best treatment appro...

    Authors: Aierken Rehemutula, Li Zhang, Lin Chen, Desong Chen and Yudong Gu
    Citation: Italian Journal of Pediatrics 2015 41:22
  29. Analyse through a multi-choice anonymous questionnaire the knowledge’s level in paediatric residents and fellows in two different main Italian hospital, looking mainly to the information to patients and relati...

    Authors: Sergio Salerno, Paola Marchese, Andrea Magistrelli, Paolo Tomà, Domenica Matranga, Massimo Midiri, Alberto G Ugazio and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2015 41:21
  30. Nemaline myopathy is a rare, non progressive congenital skeletal muscle disorder defined by the presence of inclusions known as nemaline rods in muscle fibers. Several clinical subtypes have been described, ac...

    Authors: Lucia Marseglia, Gabriella D’Angelo, Sara Manti, Vincenzo Salpietro, Teresa Arrigo, Vittorio Cavallari and Eloisa Gitto
    Citation: Italian Journal of Pediatrics 2015 41:20
  31. According to UNICEF, 40% of all under-5 deaths occur within the first month of life and half of these within the first few days of life. Many of these deaths are related to late recognition of neonatal illness...

    Authors: Uchenna Ekwochi, Ikenna K Ndu, Chidiebere DI Osuorah, Ogechukwu F Amadi, Ifeyinwa B Okeke, Ejike Obuoha, Kenechi S Onah, Ikenna Nwokoye, Odutola I Odetunde and Nnenne I Obumneme-Anyim
    Citation: Italian Journal of Pediatrics 2015 41:18
  32. Continuous glucose monitoring (CGM) originally was developed for diabetic patients and it may be a useful tool for monitoring glucose changes in pediatric intensive care unit (PICU). Its use is, however, limit...

    Authors: Gábor Marics, Levente Koncz, Katalin Eitler, Barbara Vatai, Boglárka Szénási, David Zakariás, Borbála Mikos, Anna Körner and Péter Tóth-Heyn
    Citation: Italian Journal of Pediatrics 2015 41:17
  33. Iron deficiency in infancy is associated with a range of clinical and developmentally important issues. Currently, it is unclear what is the optimal timing to administer prophylactic enteral iron supplementati...

    Authors: Hong-Xing Jin, Rong-Shan Wang, Shu-Jun Chen, Ai-Ping Wang and Xi-Yong Liu
    Citation: Italian Journal of Pediatrics 2015 41:16
  34. Familial Mediterranean fever (FMF) is an inflammatory disease, which is suggested to be associated with increased risk of atherosclerosis. Epicardial adipose tissue (EAT) thickness and the mean platelet volume...

    Authors: Ünal Uluca, Fikri Demir, Aydın Ece, Velat Şen, Ali Güneş, Fesih Aktar, İlhan Tan, Duran Karabel, Ümitcan Yazgan and Muhammed Nurullah Sabaz
    Citation: Italian Journal of Pediatrics 2015 41:15
  35. A relationship between low levels of serum vitamin D and respiratory infections has been established. No study has examined the frequency and clinical relevance of vitamin D deficiency in patients with primary...

    Authors: Virginia Mirra, Carlo Caffarelli, Marco Maglione, Rossella Valentino, Giuseppe Perruolo, Claudia Mazzarella, Laida Lisa Di Micco, Silvia Montella and Francesca Santamaria
    Citation: Italian Journal of Pediatrics 2015 41:14
  36. The prevalence of pediatric food allergy and anaphylaxis has increased in the last decades, especially in westernized countries where this emerging phenomenon was marked as a “second wave” of the allergic epid...

    Authors: Pasquale Comberiati, Francesca Cipriani, Alina Schwarz, Daniela Posa, Cristina Host and Diego G Peroni
    Citation: Italian Journal of Pediatrics 2015 41:13
  37. Hemophilia B is a rare X-linked recessive disorder with plasma factor IX (FIX) deficiency. 1-3% of patients treated with exogenous FIX-containing products develop inhibitors (i.e. polyclonal high affinity immu...

    Authors: Andrea Bon, Massimo Morfini, Alessandro Dini, Francesca Mori, Simona Barni, Sottilotta Gianluca, Maurizio de Martino and Elio Novembre
    Citation: Italian Journal of Pediatrics 2015 41:12
  38. For too long children have received medicines not sufficiently studied for their needs and, in fact, being considered as small replicas of adults, it was deemed sufficient to adjust the dosage of a drug approv...

    Authors: Maria Luisa Di Pietro, Renato Cutrera, Adele Anna Teleman and Maria Luisa Barbaccia
    Citation: Italian Journal of Pediatrics 2015 41:11
  39. Treatments for childhood obesity are critically needed because of the risk of developing co-morbidities, although the interventions are frequently time-consuming, frustrating, difficult, and expensive.

    Authors: Stefano Stagi, Elisabetta Lapi, Salvatore Seminara, Paola Pelosi, Paolo Del Greco, Laura Capirchio, Massimo Strano, Sabrina Giglio, Francesco Chiarelli and Maurizio de Martino
    Citation: Italian Journal of Pediatrics 2015 41:10
  40. Mechanical ventilation is a therapeutic action for newborns with respiratory diseases but may have side effects. Correct equipment knowledge and training may limit human errors. We aimed to test different neon...

    Authors: Ilaria Baldoli, Selene Tognarelli, Rosa T Scaramuzzo, Massimiliano Ciantelli, Francesca Cecchi, Marzia Gentile, Emilio Sigali, Paolo Ghirri, Antonio Boldrini, Arianna Menciassi, Cecilia Laschi and Armando Cuttano
    Citation: Italian Journal of Pediatrics 2015 41:9
  41. A 8-month-old child was referred to our Dermatologic Unit for suspected Neurofibromatosis type 1 (NF 1), because of the appearance, since few days after birth, of numerous café-au-lait spots (seven larger than...

    Authors: Elisa Benelli, Irene Bruno, Chiara Belcaro, Alessandro Ventura and Irene Berti
    Citation: Italian Journal of Pediatrics 2015 41:8
  42. To explore parents’ experiences and perceptions on informational, management and relational continuity of care for children with special health care needs from hospitalization to the first months after dischar...

    Authors: Elisa Zanello, Simona Calugi, Paola Rucci, Giulia Pieri, Silvia Vandini, Giacomo Faldella and Maria Pia Fantini
    Citation: Italian Journal of Pediatrics 2015 41:7
  43. Persistent pulmonary hypertension of the newborn (PPHN) is a cyanogenic plurifactorial disorder characterized by failed postnatal drop of pulmonary vascular resistance and maintenance of right-to-left shunt ac...

    Authors: Giuseppe Distefano and Pietro Sciacca
    Citation: Italian Journal of Pediatrics 2015 41:6
  44. ‘Pure’ interstitial duplication of chr6q is rare. The varying size of duplication encompassing 6q22.31 is associated with the expressivity of dysmorphism and autism. Here, we report a unique case with facial d...

    Authors: Frenny Sheth, Sunil Trivedi, Joris Andrieux, Jean-Louis Blouin and Jayesh Sheth
    Citation: Italian Journal of Pediatrics 2015 41:5
  45. The most usual presentation of Plesiomonas shigelloides infection is an acute gastroenteritis, and extraintestinal manifestations are extremely rare. We reported the first neonate with P. shigelloides meningoence...

    Authors: Fang-Qin Xia, Pei-Ning Liu and Yong-Hai Zhou
    Citation: Italian Journal of Pediatrics 2015 41:3

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