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  1. Neurocognitive disorders frequently occur in patients with cyanotic congenital heart disease (CCHD) because of the hemodynamic abnormalities induced by preoperative cardiac structural changes. We aimed to eval...

    Authors: Liang Hu, Kede Wu, Huijun Li, Meijiao Zhu, Yaqi Zhang, Mingcui Fu, Minghui Tang, Fan Lu, Xinyu Cai, Jia An, Nishant Patel, Ye Lin, Zhen Zhang, Ming Yang and Xuming Mo
    Citation: Italian Journal of Pediatrics 2024 50:189
  2. Cerebral palsy includes a spectrum of neurodevelopmental disorders caused by brain damage, leading to impairment of movement, posture, and balance for a lifetime. There are many therapeutic interventions for c...

    Authors: Panagiotis Plotas, Angelos Papadopoulos, Evangelia-Maria Apostolelli, Eleni Vlachou, Foteini Gazou, Ioanna Zogopoulou, Ioanna Katsaidoni, Ioanna Panagiotopoulou, Sofia Paraskevi Paparouna, Nikolina Silavou, Katerina Fragkiadaki, Eirini Tsiamaki, Sotirios Fouzas, Xenophon Sinopidis and Nikolaos Trimmis
    Citation: Italian Journal of Pediatrics 2024 50:188
  3. Some chromatinopathies may present with common clinical findings (intellectual disability, brain and limb malformation, facial dysmorphism). Furthermore, one of their cardinal shared features is growth dysregu...

    Authors: Elisabetta Prada, Camilla Meossi, Denise Piras Marafon, Federico Grilli, Giulietta Scuvera, Paola Giovanna Marchisio, Carlo Virginio Agostoni, Federica Natacci and Donatella Milani
    Citation: Italian Journal of Pediatrics 2024 50:187
  4. Imerslund-Gräsbeck syndrome (IGS) is a rare autosomal recessive disorder characterized by megaloblastic anemia due to selective cobalamin malabsorption and benign proteinuria. IGS is caused by a disfunction of...

    Authors: Francesca Di Sario, Francesca Piloni, Francesco Gasparini, Eleonora Serpetti, Barbara Bruschi, Paola Coccia, Maria Elena Lionetti and Simona Gatti
    Citation: Italian Journal of Pediatrics 2024 50:186
  5. Echocardiography-based ultrasomics analysis aids Kawasaki disease (KD) diagnosis but its role in predicting coronary artery lesions (CALs) progression remains unknown. We aimed to develop and validate a predic...

    Authors: Dan Xu, Chen-Hui Feng, Ai-Mei Cao, Shuai Yang, Zhen-Chao Tang and Xiao-Hui Li
    Citation: Italian Journal of Pediatrics 2024 50:185
  6. Neonatal Marfan syndrome (nMFS) is a rare condition characterized by severe phenotype and poor prognosis. nMFS is caused by mutations in a specific region of the fibrillin 1 gene (FBN1). Prompt recognition of ...

    Authors: Flaminia Pugnaloni, Domenico Umberto De Rose, Maria Cristina Digilio, Monia Magliozzi, Annabella Braguglia, Laura Valfrè, Alessandra Toscano, Andrea Dotta and Alessandra Di Pede
    Citation: Italian Journal of Pediatrics 2024 50:183
  7. Pentraxin 3 (PTX3) is an acute-phase reactant that is elevated in the plasma during inflammatory responses. We aimed to evaluate the utility of PTX3 as a clinical marker in children with lower respiratory trac...

    Authors: Shaimaa Madkour, Mona Gamal Mostafa and Huda El-Kady
    Citation: Italian Journal of Pediatrics 2024 50:182
  8. In developing countries birth asphyxia is a major cause of neonatal morbidity and mortality. Despite the implementation of various strategies and interventions to combat neonatal mortality rates, birth asphyxi...

    Authors: Dawit Tarko, Tesfu Zewdu, Shewamene Tesfaye, Abel Gerezihear and Azeb Haile
    Citation: Italian Journal of Pediatrics 2024 50:181
  9. Exclusive breastfeeding during postpartum hospitalization is very important for ensuring the success of breastfeeding at home. The aim of the study is to determine if the on-site nurse in rooming in improves e...

    Authors: Giuseppe Latorre, Domenico Martinelli, Manuela Capozza, Francesca Maria Grosso, Nicola Laforgia and Maria Elisabetta Baldassarre
    Citation: Italian Journal of Pediatrics 2024 50:180
  10. External Jugular Thrombophlebitis (EJT) is a rare clinical phenomenon with few reports in the literature, especially in the pediatric population. This is a report of an unusual case of right-sided EJT in a ped...

    Authors: Uche C. Ezeh, Naomi Tesema, Sukaina Hasnie, Philip J. Kahn and Max M. April
    Citation: Italian Journal of Pediatrics 2024 50:179
  11. To evaluate the impact of implementation of 2019 European respiratory distress syndrome (RDS) guidelines on the incidence of bronchopulmonary dysplasia (BPD).

    Authors: Chongbing Yan, Xiaohui Gong, Hao Luo, Yibo Liu, Yating Lin, Bowen Weng and Cheng Cai
    Citation: Italian Journal of Pediatrics 2024 50:178
  12. Despite the worldwide increasing incidence of Group A Streptococcus (GAS) infections reported since December 2022, data on noninvasive GAS (nGAS) infections in the post COVID-19 era are limited. By a self-repo...

    Authors: Bianca Laura Cinicola, Ilaria Sani, Federica Pulvirenti, Martina Capponi, Fabrizio Leone, Alberto Spalice, Agata Montalbano, Alessandra Macari, Maria Teresa Fonte, Paolo Gianni Giampietro, Danilo Buonsenso, Anna Maria Zicari and Teresa Rongai
    Citation: Italian Journal of Pediatrics 2024 50:177
  13. Reports on coronavirus disease 2019 (COVID-19) in neonates are limited, especially in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) Omicron variant. This study aims to ana...

    Authors: Huijing Wei, Fu Wei, Xiaokang Peng, Pan Liu, Li Tang, Yishan Liu, Shan Liao, Yajing Bo, Yuzhen Zhao, Ruina Li, Xiaoguai Liu and Fanpu Ji
    Citation: Italian Journal of Pediatrics 2024 50:176
  14. Group B Streptococcus (GBS) is a major cause of sepsis and meningitis in newborns. The Centers for Disease Control and Prevention (CDC) recommends to pregnant women, between 35 and 37 weeks of gestation, universa...

    Authors: Gregorio Serra, Lucia Lo Scalzo, Maria Giordano, Mario Giuffrè, Pietro Trupiano, Renato Venezia and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2024 50:175
  15. This study aimed to compare targeted next-generation sequencing (tNGS) with metagenomic next-generation sequencing (mNGS) for pathogen detection in infants with severe postoperative pneumonia after congenital ...

    Authors: Yi-Rong Zheng, Xiu-Hua Chen, Qiang Chen and Hua Cao
    Citation: Italian Journal of Pediatrics 2024 50:174
  16. The cycle threshold (Ct) value is inversely proportional to the number of copies of the target region in a sample, suggesting that a low Ct value indicates a high pathogen load. The relationship between Ct val...

    Authors: Wen Li, Huaping Wang, Shu Teng, Yalin Sun, Qi Jia, Zhenghong Qi, Lingbo Wang, Zhangnv Yang and Shiyong Zhao
    Citation: Italian Journal of Pediatrics 2024 50:173
  17. This study aimed to investigate the clinical and molecular genetic characteristics of ten children with ornithine carbamoyltransferase deficiency (OTCD) in southeastern China, as well as the correlation betwee...

    Authors: Gaopin Yuan, Zhiyong Liu, Zhixu Chen, Xiaohong Zhang, Weifeng Zhang and Dongmei Chen
    Citation: Italian Journal of Pediatrics 2024 50:171
  18. This study delves into the risk perceptions of Italian pediatricians concerning climate change's impact on children's health. Given children's heightened vulnerability to climate-related health risks, comprehe...

    Authors: Sara Moraca, Luciana Indinnimeo and Paola De Nuntiis
    Citation: Italian Journal of Pediatrics 2024 50:170
  19. Neonatal hypoxic ischemic encephalopathy (HIE) leads to different degrees of neurological sequelae. The incidence of HIE is relatively high, and the causal pathways leading to HIE are still controversial. This...

    Authors: Yiran Wang, Yaodong Zhang, Shuying Luo and Kaijuan Wang
    Citation: Italian Journal of Pediatrics 2024 50:169
  20. At present, preterm infants with respiratory distress syndrome (RDS) in China present higher mortality and morbidity rates than those in high-income countries. The aim of this nationwide survey was to assess t...

    Authors: Long Chen, Yong Ji, Rong Ju, Jiang-Qin Liu, Ling Liu, Jingyun Shi, Hui Wu, Lili Wang, Falin Xu, Chuanzhong Yang, Huayan Zhang and Yuan Shi
    Citation: Italian Journal of Pediatrics 2024 50:168
  21. The significant impact of acute respiratory tract infections on healthcare systems is well-documented, given their contribution to emergency department admissions, hospitalizations, and increased use of antibi...

    Authors: Riccardo Boracchini, Benedetta Canova, Pietro Ferrara, Luigi Cantarutti, Carlo Giaquinto, Costanza Di Chiara and Anna Cantarutti
    Citation: Italian Journal of Pediatrics 2024 50:167
  22. Positional plagiocephaly is an asymmetrical flattened skull deformity whose incidence increased significantly in the last decades. Osteopathic treatment has been suggested to tackle early deformational sequenc...

    Authors: Raffaella Panza, Filippo Piarulli, Valentina Rizzo, Federico Schettini, Maria Elisabetta Baldassarre, Antonio Di Lorenzo, Silvio Tafuri and Nicola Laforgia
    Citation: Italian Journal of Pediatrics 2024 50:166
  23. Human Immune deficiency Virus (HIV) infected children are at higher risk of developing pneumonia. Particularly, in the early phase of HIV infection, the risk of acquiring pneumonia is high, and it remains a ma...

    Authors: Gebrehiwot Berie Mekonnen, Fikadie Dagnew Baye, Gashaw Kerebeh, Mengistu Melak Fekadie, Yohannes Tesfahun Kassie, Tiruye Azene Demile, Alamirew Enyew Belay, Asnake Gashaw Belayneh, Bruck Tesfaye Legesse, Wubet Tazeb Wondie and Mengistu Abebe Messelu
    Citation: Italian Journal of Pediatrics 2024 50:165
  24. Recently, the development of advanced, noninvasive methods has allowed the study of respiratory function even in uncooperative infants. To date, there is still little data on the application of this technique ...

    Authors: Silvia Bloise, Raffaella Nenna, Laura Petrarca, Maria Giulia Conti, Greta Di Mattia, Luigi Matera, Enrica Mancino, Domenico Paolo La Regina, Riccardo Lubrano, Enea Bonci, Corrado Moretti and Fabio Midulla
    Citation: Italian Journal of Pediatrics 2024 50:164
  25. Systemic Lupus Erythematosus (SLE) patients are more likely than the general population to suffer from thyroid illness. The major goal was to assess the thyroid dysfunctions due to immunological factors in Egy...

    Authors: Radwa Ahmed Shamma, Hend Mehawed Soliman, Walaa Abdelfattah, Marwa Ahmed Badawy and Eman Shafik Shafie
    Citation: Italian Journal of Pediatrics 2024 50:163
  26. Carboxylesterase 1(CES1) is expressed mainly in the liver and adipose tissue and is highly hypothesized to play an essential role in metabolism. Our study aimed to investigate the association between CES1 and ...

    Authors: Huanyu Wang, Shimin Wu, Ying Weng, Xi Yang, Ling Hou, Yan Liang, Wei Wu, Yanqin Ying, Feng Ye and Xiaoping Luo
    Citation: Italian Journal of Pediatrics 2024 50:162
  27. Elevated lipoprotein (Lp(a)) levels are associated with increased risk of atherosclerotic processes and cardiovascular events in adults. The amount of Lp(a) is mainly genetically determined. Therefore, it is i...

    Authors: Marco Giussani, Antonina Orlando, Elena Tassistro, Erminio Torresani, Giulia Lieti, Ilenia Patti, Claudia Colombrita, Ilaria Bulgarelli, Laura Antolini, Gianfranco Parati and Simonetta Genovesi
    Citation: Italian Journal of Pediatrics 2024 50:161
  28. Authors: Renato Cutrera, Daniela d’Angela, Massimiliano Orso, Liliana Guadagni, Anna Chiara Vittucci, Ilaria Bertoldi, Barbara Polistena, Federico Spandonaro, Ciro Carrieri, Eva Agostina Montuori, Raffaella Iantomasi and Luigi Orfeo
    Citation: Italian Journal of Pediatrics 2024 50:160

    The original article was published in Italian Journal of Pediatrics 2024 50:119

  29. Consistent evidence increasingly highlights the significance of integrating sex and gender medicine to ensure a precision approach according to individual patient needs. Gender discrepancies emerge across vari...

    Authors: Veronica Maria Tagi, Giulia Fiore, Chiara Tricella, Francesca Eletti, Alessandro Visioli, Federica Bona, Gianvincenzo Zuccotti, Antonio Corsello and Elvira Verduci
    Citation: Italian Journal of Pediatrics 2024 50:159
  30. Contactin-associated protein-2(CASPR2) antibody-associated autoimmune encephalitis(AE) is rare in children. This study aimed to report the clinical characteristics and long-term outcome of CASPR2 autoimmunity ...

    Authors: Donglei Liao, Saying Zhu, Lifen Yang, Ciliu Zhang, Fang He, Fei Yin and Jing Peng
    Citation: Italian Journal of Pediatrics 2024 50:158
  31. Spinal muscular atrophy (SMA) is an autosomal recessive motor neuron disease that leads to multiple organ dysfunction. The advent of disease-modifying treatments makes the early diagnosis of SMA critical. Heal...

    Authors: Weiran Zhang, Yijie Feng, Yue Yan, Mei Yao, Feng Gao, Wei Lin and Shanshan Mao
    Citation: Italian Journal of Pediatrics 2024 50:157
  32. Dilated cardiomyopathy (DCM) is an etiologically heterogeneous group of diseases of the myocardium. With the rapid evolution in laboratory investigations, genetic background is increasingly determined includin...

    Authors: Irene Picciolli, Angelo Ratti, Berardo Rinaldi, Anwar Baban, Maria Iascone, Gaia Francescato, Alessia Cappelleri, Monia Magliozzi, Antonio Novelli, Giovanni Parlapiano, Anna Maria Colli, Nicola Persico, Stefano Carugo, Fabio Mosca and Maria Francesca Bedeschi
    Citation: Italian Journal of Pediatrics 2024 50:156
  33. This study aims to analyse changes in urinary kidney injury markers in children with Mycoplasma pneumoniae pneumonia (MPP), investigate the risk factors for MPP-related acute kidney injury (AKI) and establish a m...

    Authors: Ju Zhang, He-kai Ma, Bao-wen Li, Ke-Ke Ma, Yu-Ling Zhang and Shu-jun Li
    Citation: Italian Journal of Pediatrics 2024 50:155
  34. Spinal muscular atrophy (SMA) is a neurodegenerative disorder. Although prior studies have investigated the metabolomes of SMA in various contexts, there is a gap in research on cerebrospinal fluid (CSF) metab...

    Authors: Wei Zhuang, Minying Wang, Mei Lu, Zhehui Chen, Meifen Luo, Wanlong Lin and Xudong Wang
    Citation: Italian Journal of Pediatrics 2024 50:154
  35. Transposition of the great arteries (TGA) is the most common cyanotic congenital heart defect in neonates but with low prenatal detection rate. This study sought to review the prenatal diagnosis, associated ab...

    Authors: Xieyi Lin, Ying Huang, Wen Xie, Lu Chen, Yuping Huang, Yu Huang, Bingyu Ma, Shusheng Wen and Wei Pan
    Citation: Italian Journal of Pediatrics 2024 50:153
  36. A systematic analysis was conducted to investigate the molecular etiology of fetal cleft lip and/or palate (CL/P) and the association between various types of CL/P and copy number variations (CNVs), as well as...

    Authors: Shujuan Yan, Qiuxia Yu, Hang Zhou, Ruibin Huang, You Wang, Chunling Ma, Fei Guo, Fang Fu, Ru Li, Fucheng Li, Xiangyi Jin, Li Zhen, Min Pan, Dongzhi Li and Can Liao
    Citation: Italian Journal of Pediatrics 2024 50:152
  37. Increases in migration patterns in the recent years have led to a continuously growing number of unaccompanied foreign minors (UFMs) entering Italy. As part of processing and integration, age assessment is per...

    Authors: Danilo Buonsenso, Manuela Ceccarelli, Bettina Camara, Donatella Angelone, Valentina Burzio, Simona La Placa and Piero Valentini
    Citation: Italian Journal of Pediatrics 2024 50:151
  38. Childhood obesity has become a major global health problem. Obesity is associated with major health problems, such as diabetes, hypertension, dyslipidemia, cardiovascular disease. Obesity is also considered a ...

    Authors: Yakup Çağ, Safiye Güneş Sağer, Merve Akçay, İsmail Kaytan, Elif Söbü, Aydan Erdem and Yasemin Akın
    Citation: Italian Journal of Pediatrics 2024 50:150
  39. Childhood-onset systemic lupus erythematosus (c-SLE) is a multifaceted autoimmune disorder predominantly affecting the musculoskeletal (MSK) system. This investigation delineated the spectrum and sequelae of M...

    Authors: Maynart Sukharomana, Siritida Vonginyoo, Nuntawan Piyaphanee and Sirirat Charuvanij
    Citation: Italian Journal of Pediatrics 2024 50:149
  40. Fever in children represents one of the most common causes of medical evaluation. Infants younger than 90 days of age are at higher risk of severe and invasive bacterial infections (SBI and IBI). However, clin...

    Authors: Giulia Brigadoi, Francesca Tirelli, Sara Rossin, Veronica Casotto, Francesca Riello, Giulia Gallinaro, Daniele Donà, Silvia Bressan and Liviana Da Dalt
    Citation: Italian Journal of Pediatrics 2024 50:148
  41. Central venous catheters (CVCs) are the major risk factors for neonatal thrombosis that might negatively affect morbidity and mortality in neonates. The aim of the present work was to estimate the incidence of...

    Authors: Marwa Mohamed Farag, Hesham Abd El Rahim Ghazal, Mohamed Masoud Radwan and Nada Saeid El-sayed
    Citation: Italian Journal of Pediatrics 2024 50:147
  42. Working mothers are in a situation where they have to manage both their job and maternal roles simultaneously. We aim to show the relationship between mothers' breastfeeding behavior and working status, as wel...

    Authors: Şeyma ÇİÇEK, Siddika Songül YALÇIN, Mehmet Ali ERYURT and Suzan YALÇIN
    Citation: Italian Journal of Pediatrics 2024 50:146
  43. Idiopathic anaphylaxis (IA) remains a frustrating challenge for both patients and physicians. The aim of this paper is to focus on IA in pediatric ages and suggest possible diagnostic algorithms according to s...

    Authors: Francesca Mori, Francesca Saretta, Mattia Giovannini, Mariannita Gelsomino, Lucia Liotti, Simona Barni, Carla Mastrorilli, Luca Pecoraro, Riccardo Castagnoli, Stefania Arasi, Lucia Caminiti, Angela Klain, Michele Miraglia del Giudice and Elio Novembre
    Citation: Italian Journal of Pediatrics 2024 50:145
  44. Psychopathological disorders are often comorbid diagnosis in eating disorders (EDs). We aimed to assess the presence of psychopathological traits and symptoms associated with EDs in an Italian high school adol...

    Authors: Valeria Calcaterra, Vittoria Carlotta Magenes, Martina Basso, Veronica Conte, Giulia Maggioni, Susanna Russo, Annalisa De Silvestri, Valentina Fabiano, Elisabetta Agnese Marrocco, Pierangelo Veggiotti and Gianvincenzo Zuccotti
    Citation: Italian Journal of Pediatrics 2024 50:144
  45. John M. Opitz, a towering figure in both stature and scientific achievement, left an indelible mark on the fields of genetics, pediatrics, and embryology. Born in 1935 in Hamburg to a Jewish family, Opitz’s ea...

    Authors: Lorenzo Pavone, Giovanni Corsello and Martino Ruggieri
    Citation: Italian Journal of Pediatrics 2024 50:143
  46. Preterm infants are at high risk for retinopathy of prematurity (ROP), with potential life-long visual impairment. Low fetal hemoglobin (HbF) levels predict ROP. It is unknown if preventing the HbF decrease al...

    Authors: Luciana Teofili, Patrizia Papacci, Carlo Dani, Francesco Cresi, Giulia Remaschi, Claudio Pellegrino, Maria Bianchi, Giulia Ansaldi, Maria Francesca Campagnoli, Barbara Vania, Domenico Lepore, Fabrizio Gaetano Saverio Franco, Marco Fabbri, Roberta Penta de Vera d’ Aragona, Anna Molisso, Enrico Beccastrini…
    Citation: Italian Journal of Pediatrics 2024 50:142
  47. Wilms tumor (WT) survival has been affected by the evolution in clinical and biological prognostic factors. Significant differences in survival rates indicate the need for further efforts to reduce these dispa...

    Authors: Anas Elgenidy, Ahmed M. Afifi, Eman F. Gad, Hoda Atef Abdelsattar Ibrahim, Ubaid khan, Omar Alomari, Huzaifa A. Cheema, Mohammad Ebad-Ur-Rehman, Aya Sherif, Mohammad Alzu’bi, Mohamed Abd-Elfattah, Ahmad Roshdy Ahmad, Amira Elhoufey, Amira M. Osman, Mohamed Ezzat, Ahmed E. Hammour…
    Citation: Italian Journal of Pediatrics 2024 50:141
  48. Pediatric asthma management is a compelling challenge for every pediatrician. Different aspects require attention and definition. The present Intersocietal Survey aimed to collect real-world experiences from a...

    Authors: Maria Angela Tosca, Antonio D’Avino, Giuseppe Di Mauro, Gian Luigi Marseglia, Michele Miraglia del Giudice and Giorgio Ciprandi
    Citation: Italian Journal of Pediatrics 2024 50:140

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