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  1. A 8 month-old infant presented with acute onset of severe jaundice, anemia requiring transfusion and Glucose-6-Phosphate Dehydrogenase deficiency. The infant did not take drugs, he did not consume fava beans, ...

    Authors: Gian Vincenzo Zuccotti, Francesca Redaelli, Valentina Gualdi, Valeria Rizzi, Chiara Mameli, Dario Dilillo and Valentina Fabiano
    Citation: Italian Journal of Pediatrics 2014 40:71
  2. Early discharge of mother/neonate dyad has become a common practice, and its effects are measured by readmission rates. We evaluated the safety of early discharge followed by an individualized Follow-up progra...

    Authors: Maria Pia De Carolis, Carmen Cocca, Elisabetta Valente, Serafina Lacerenza, Serena Antonia Rubortone, Antonio Alberto Zuppa and Costantino Romagnoli
    Citation: Italian Journal of Pediatrics 2014 40:70
  3. Suicidal behaviors are among the leading causes of death worldwide. The large spread of suicide suggests that educational programs and literature to parents or guardians should include information about the po...

    Authors: Pietro Ferrara, Francesca Ianniello, Costanza Cutrona, Fabio Quintarelli, Flaminia Vena, Valentina Del Volgo, Olga Caporale, Monica Malamisura, Maria Chiara De Angelis, Antonio Gatto, Antonio Chiaretti and Riccardo Riccardi
    Citation: Italian Journal of Pediatrics 2014 40:69
  4. This review will provide new information related to pathophysiology and management of specific diseases that have been addressed by selected articles published in the Italian Journal of Pediatrics in 2013, focusi...

    Authors: Carlo Caffarelli, Francesca Santamaria, Alessandra Vottero, Carlotta Povesi Dascola, Virginia Mirra, Francesco Sperli and Sergio Bernasconi
    Citation: Italian Journal of Pediatrics 2014 40:62
  5. Several neuromotor disorders share exclusive, although often overlooked, nutritional problems. The objective of this study is therefore to delineate the frequency of malnutrition, evaluate the effectiveness of...

    Authors: Maria Sangermano, Roberta D’Aniello, Grazia Massa, Raffaele Albano, Pasquale Pisano, Mauro Budetta, Goffredo Scuccimarra, Enrico Papa, Giangennaro Coppola and Pietro Vajro
    Citation: Italian Journal of Pediatrics 2014 40:61
  6. Current literature provides limited data on the hemodynamic changes that may occur during bi-level continuous positive airway pressure (CPAP) support in preterm infants. However, the application of a positive ...

    Authors: Giulia Aquilano, Silvia Galletti, Arianna Aceti, Francesca Vitali and Giacomo Faldella
    Citation: Italian Journal of Pediatrics 2014 40:60
  7. Neurofibromatosis type 1 (NF1) is the most prevalent autosomal dominant genetic disorder among humans. NF1 vasculopathy is a significant but underrecognized complication of the disease, affecting both arterial...

    Authors: Euthymia Vargiami, Evdoxia Sapountzi, Dimitris Samakovitis, Spyros Batzios, Maria Kyriazi, Athanasia Anastasiou and Dimitrios I Zafeiriou
    Citation: Italian Journal of Pediatrics 2014 40:59
  8. Acute cerebellitis (AC) is the most common neurological complication of varicella. Nevertheless, it has been scarcely studied. The objective of this study were to asses the occurrence of AC among children hosp...

    Authors: Elena Bozzola, Mauro Bozzola, Alberto Eugenio Tozzi, Valeria Calcaterra, Daniela Longo, Andrzej Krzystofiak and Alberto Villani
    Citation: Italian Journal of Pediatrics 2014 40:57
  9. Cough is an extremely common problem in pediatrics, mostly triggered and perpetuated by inflammatory processes or mechanical irritation leading to viscous mucous production and increased sensitivity of the cou...

    Authors: Mario Canciani, Vitalia Murgia, Davide Caimmi, Sreedhar Anapurapu, Amelia Licari and Gian Luigi Marseglia
    Citation: Italian Journal of Pediatrics 2014 40:56
  10. In recent years, as knowledge regarding the etiopathogenetic mechanisms of bone involvement characterizing many diseases has increased and diagnostic techniques evaluating bone health have progressively improv...

    Authors: Stefano Stagi, Loredana Cavalli, Salvatore Seminara, Maurizio de Martino and Maria Luisa Brandi
    Citation: Italian Journal of Pediatrics 2014 40:55
  11. Vitamin D plays an important role in health promotion during adolescence. Vitamin D deficiency and insufficiency are common in adolescents worldwide. Few data on vitamin D status and risk factors for hypovitam...

    Authors: Francesco Vierucci, Marta Del Pistoia, Margherita Fanos, Paola Erba and Giuseppe Saggese
    Citation: Italian Journal of Pediatrics 2014 40:54
  12. Infantile colic is a common disturbance occurring in the first three months of life. It is a benign condition and one of the main causes of pediatric consultation in the early part of life because of its great...

    Authors: Francesco Savino, Simone Ceratto, Angela De Marco and Luca Cordero di Montezemolo
    Citation: Italian Journal of Pediatrics 2014 40:53
  13. To evaluate short-term respiratory outcomes in late preterm infants (LPI) compared with those of term infants (TI).

    Authors: Miria Natile, Maria Luisa Ventura, Marco Colombo, Davide Bernasconi, Anna Locatelli, Cristina Plevani, Maria Grazia Valsecchi and Paolo Tagliabue
    Citation: Italian Journal of Pediatrics 2014 40:52
  14. CHARGE association is characterized by ocular Coloboma, Heart malformations, choanal Atresia, Retardation of growth and development, Genital abnormalities and inner and external Ear abnormalities. Growth failu...

    Authors: Andrea Esposito, Maria Tufano, Iolanda Di Donato, Martina Rezzuto, Nicola Improda, Daniela Melis and Mariacarolina Salerno
    Citation: Italian Journal of Pediatrics 2014 40:51
  15. The aim of our study was to evaluate factors affecting cystic fibrosis (CF) patients’ health-related quality of life (HRQoL) and to assess the level of agreement on HRQol between children and their parents.

    Authors: Reka Bodnar, Laszlo Kadar, Klara Holics, Rita Ujhelyi, Lajos Kovacs, Katalin Bolbas, Gyongyi Szekely, Kalman Gyurkovits, Eniko Solyom and Agnes Meszaros
    Citation: Italian Journal of Pediatrics 2014 40:50
  16. Aims of this commentary is to report the most recent views about epidemiology, diagnostic procedures, malignancy risk factors and clinical management of thyroid nodules in children. On the basis of our persona...

    Authors: Filippo De Luca, Tommaso Aversa, Luca Alessi, Valeria Cama, Daria Costanzo, Cristina Genovese, Veronica Scuderi, Roberta Vadalà and Giuseppe Zoccali
    Citation: Italian Journal of Pediatrics 2014 40:48
  17. It has been shown that nasal saline irrigation (NSI) alone can be effective in children with infectious and/or allergic respiratory problems, but no study has assessed the awareness or clinical use of NSI amon...

    Authors: Paola Marchisio, Marina Picca, Sara Torretta, Elena Baggi, Angela Pasinato, Sonia Bianchini, Erica Nazzari, Susanna Esposito and Nicola Principi
    Citation: Italian Journal of Pediatrics 2014 40:47
  18. Atopic dermatitis (AD) is a chronic inflammatory skin disease and can be the first step of the atopic march.

    Authors: Giampaolo Ricci, Arianna Dondi, Iria Neri, Lorenza Ricci, Annalisa Patrizi and Andrea Pession
    Citation: Italian Journal of Pediatrics 2014 40:46
  19. Neutropenia encompasses a family of neutropenic disorders, both permanent and intermittent, ranging from severe (<500 neutrophils/mm3) to mild (500–1500 neutrophils/mm3), which may also affect other organ systems...

    Authors: Veronica Folsi, Nunzia Miglietti, Annamaria Lombardi, Sara Boccacci, Tatiana Utyatnikova, Chiara Donati, Livia Squassabia, Laura Gazzola, Ilaria Bosio, Adele Borghi, Veronica Grassi, Lucia D Notarangelo and Alessandro Plebani
    Citation: Italian Journal of Pediatrics 2014 40:45
  20. Young children are using digital technology (DT) devices anytime and anywhere, especially with the invention of smart phones and the replacement of desktop computers with digital tablets. Although research has...

    Authors: Cynthia Sau Ting Wu, Cathrine Fowler, Winsome Yuk Yin Lam, Ho Ting Wong, Charmaine Hei Man Wong and Alice Yuen Loke
    Citation: Italian Journal of Pediatrics 2014 40:44
  21. Twins, compared to singletons, have an increased risk of perinatal mortality and morbidity, due mainly to a higher prevalence of preterm birth and low birthweight. Intrauterine growth restriction (IUGR) is als...

    Authors: Giuseppe Puccio, Mario Giuffré, Maria Piccione, Ettore Piro, Valentina Malerba and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2014 40:43
  22. Small dense low density lipoprotein-cholesterol (sdLDL-C) molecules are more atherogenic compared with large buoyant ones. Phytosterols-enriched diets are effective in decreasing total cholesterol (TC) and low...

    Authors: Anastasia Garoufi, Styliani Vorre, Alexandra Soldatou, Charalampos Tsentidis, Lydia Kossiva, Antonios Drakatos, Antonios Marmarinos and Dimitrios Gourgiotis
    Citation: Italian Journal of Pediatrics 2014 40:42
  23. Ability to maintain a normal body temperature in an open crib is an important physiologic competency generally requested to discharge preterm infants from the hospital. The aim of this study is to assess the f...

    Authors: Giovanni Barone, Mirta Corsello, Patrizia Papacci, Francesca Priolo, Costantino Romagnoli and Enrico Zecca
    Citation: Italian Journal of Pediatrics 2014 40:41
  24. The best criteria for surfactant treatment in the perinatal period are unknown and this makes it of interest to consider the possible economic implications of lessening the use of more restrictive criteria.

    Authors: Carlo Dani, Roberto Ravasio, Leonardo Fioravanti and Maria Circelli
    Citation: Italian Journal of Pediatrics 2014 40:40
  25. Array comparative genomic hybridization (a-CGH) has become the first-tier investigation in patients with unexplained developmental delay/intellectual disability (DD/ID). Although the costs are progressively de...

    Authors: Elisa Caramaschi, Ilaria Stanghellini, Pamela Magini, Maria Grazia Giuffrida, Silvia Scullin, Tiziana Giuva, Patrizia Bergonzini, Azzurra Guerra, Paolo Paolucci and Antonio Percesepe
    Citation: Italian Journal of Pediatrics 2014 40:39
  26. Aim of this study was to obtain a picture of the nature of the primary care pediatricians’ visits during a winter season. We investigated reasons for visits, diagnosis, and pattern of prescription in 284 child...

    Authors: Antonietta Giannattasio, Andrea Lo Vecchio, Carmen Napolitano, Laura Di Florio and Alfredo Guarino
    Citation: Italian Journal of Pediatrics 2014 40:38
  27. There are few prospective evaluations of point-of-care ultrasonography (US) for the diagnosis of pediatric community-acquired pneumonia (CAP). In particular, there are very few data concerning the efficiency o...

    Authors: Susanna Esposito, Simone Sferrazza Papa, Irene Borzani, Raffaella Pinzani, Caterina Giannitto, Dario Consonni and Nicola Principi
    Citation: Italian Journal of Pediatrics 2014 40:37
  28. Hypereosinophilia as first clinical presentation has rarely been reported in paediatric acute lymphoblastic leukaemia. It is commonly associated with specific cytogenetic abnormalities. Although eosinophilia i...

    Authors: Rosanna Parasole, Fara Petruzziello, Antonia De Matteo, Giovanna Maisto, Luisa Castelli, Maria Elena Errico, Giuseppe Menna and Vincenzo Poggi
    Citation: Italian Journal of Pediatrics 2014 40:36
  29. Idiopathic pulmonary hemosiderosis is a rare disorder that can occur at any age and is characterized by the triad of hemoptysis, iron deficiency anemia and diffuse pulmonary infiltrates. The clinical course is...

    Authors: Ilirjana Bakalli, Luljeta Kota, Durim Sala, Ermela Celaj, Elmira Kola, Robert Lluka and Sashenka Sallabanda
    Citation: Italian Journal of Pediatrics 2014 40:35
  30. Mitochondrial dysfunction accounts for a large group of inherited metabolic disorders most of which are due to a dysfunctional mitochondrial respiratory chain (MRC) and, consequently, deficient energy producti...

    Authors: Célia Nogueira, Ligia S Almeida, Claudia Nesti, Ilaria Pezzini, Arnaldo Videira, Laura Vilarinho and Filippo M Santorelli
    Citation: Italian Journal of Pediatrics 2014 40:34
  31. Although individual occurrence is rare, syndromic obesity with mental retardation has been reported in conjunction with 140 different diseases.

    Authors: Donatella Milani, Marta Cerutti, Lidia Pezzani, Pietro Maffei, Gabriella Milan and Susanna Esposito
    Citation: Italian Journal of Pediatrics 2014 40:33
  32. Gut microbiota plays a significant role in human health and energy balance, and provides protection against disease states. An altered balance between microbiota and its host (dysbiosis) would appear to contri...

    Authors: Donatella Comito, Antonio Cascio and Claudio Romano
    Citation: Italian Journal of Pediatrics 2014 40:32
  33. During the last century, mass vaccination programs have achieved considerable success across the world in immunizing against several serious infectious diseases. However, vaccinations are threatened by their o...

    Authors: Luciana Nicolosi, Annachiara Vittucci, Rossella Mancini, Elena Bozzola, Alberto Cagigi, Annalisa Grandin and Alberto Villani
    Citation: Italian Journal of Pediatrics 2014 40:31
  34. Glycogen storage disease type 1b (GSD1b) is an inherited metabolic defect of glycogenolysis and gluconeogenesis due to mutations of the SLC37A4 gene and to defective transport of glucose-6-phosphate. The clini...

    Authors: Daniela Melis, Roberto Della Casa, Francesca Balivo, Giorgia Minopoli, Alessandro Rossi, Mariacarolina Salerno, Generoso Andria and Giancarlo Parenti
    Citation: Italian Journal of Pediatrics 2014 40:30
  35. The low uptake of tetanus vaccine and its resultant high burden of tetanus in Nigeria suggest the need to improve routine and booster vaccination in children and adolescents. However, epidemiological evidence ...

    Authors: Adebola E Orimadegun, Akinlolu A Adepoju and Olusegun O Akinyinka
    Citation: Italian Journal of Pediatrics 2014 40:29
  36. Intussusception remains a common cause of bowel obstruction in children and results in significant morbidity and mortality if not promptly treated. There is a paucity of prospective studies regarding childhood...

    Authors: Phillipo L Chalya, Neema M Kayange and Alphonce B Chandika
    Citation: Italian Journal of Pediatrics 2014 40:28
  37. Surfactant treatment reduces respiratory morbidity and mortality in preterm infants. Data on its haemodynamic consequences are conflicting. The aim was to characterise the haemodynamic effects of surfactant tr...

    Authors: Francesca Vitali, Silvia Galletti, Arianna Aceti, Giulia Aquilano, Marianna Fabi, Anna Balducci and Giacomo Faldella
    Citation: Italian Journal of Pediatrics 2014 40:26
  38. Orbital cellulitis is an infrequent complication of acute ethmoiditis possibly leading to life- or visual-threatening complications. Despite its natural history is well known, its clinical evolution may widely...

    Authors: Sara Torretta, Paola Marchisio, Michele Gaffuri, Pasquale Capaccio, Susanna Esposito and Lorenzo Pignataro
    Citation: Italian Journal of Pediatrics 2014 40:25
  39. We describe a girl with Turner syndrome, a genetic disorder of the X chromosome in a phenotypic female at increased risk of autoimmune and immunological diseases, who developed Kawasaki disease at the age of f...

    Authors: Stefano Stagi, Stefania Losi, Francesco Chiarelli, Maurizio de Martino and Fernanda Falcini
    Citation: Italian Journal of Pediatrics 2014 40:24
  40. Aim of our study is to analyze the immunological status in pregnancy for two main TORCH agents, Toxoplasma and Cytomegalovirus (CMV), and the results of group B streptococcus (GBS) screening, assessing the ris...

    Authors: Giuseppe Puccio, Cinzia Cajozzo, Laura Antonella Canduscio, Lucia Cino, Amelia Romano, Maria Gabriella Schimmenti, Mario Giuffrè and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2014 40:23
  41. Asthma is the result of a complex interaction between environmental factors and genetic variants that confer susceptibility. The glutathione S-transferases (GSTT1 and GSTM1) are phase II enzymes thought to pro...

    Authors: Nihal El Rifai, Nadia Moustafa, Nelly Degheidy and Manal Wilson
    Citation: Italian Journal of Pediatrics 2014 40:22
  42. Inhibitors of the cyclo-oxygenase component of prostaglandin-H2 synthetase, namely indomethacin and ibuprofen, are commonly used in the treatment of hemodynamically significant patent ductus arteriosus. These dru...

    Authors: Gianluca Terrin, Francesca Conte, Antonella Scipione, Erica Bacchio, Maria Giulia Conti, Rosalia Ferro, Flavia Ventriglia and Mario De Curtis
    Citation: Italian Journal of Pediatrics 2014 40:21
  43. To date, only a few studies on child obesity concerned Trace Elements (TE). TE is involved in the pathogenesis of obesity and obesity related diseases. We tried to assess trace elements status [zinc (Zn), copp...

    Authors: Seham FA Azab, Safaa H Saleh, Wafaa F Elsaeed, Mona A Elshafie, Laila M Sherief and Asmaa MH Esh
    Citation: Italian Journal of Pediatrics 2014 40:20
  44. The aim of this study is to examine the prevalence of behavioural and emotional problems in a sample of school children living in Campania, a region of South Italy.

    Authors: Antonella Gritti, Carmela Bravaccio, Simona Signoriello, Filomena Salerno, Simone Pisano, Gennaro Catone, Ciro Gallo and Antonio Pascotto
    Citation: Italian Journal of Pediatrics 2014 40:19
  45. Plastic bronchitis is a rare complication of a variety of respiratory diseases and congenital heart disease surgery, particularly Fontan procedure. Bronchial casts with rubber-like consistency develop acutely ...

    Authors: Massimo Colaneri, Andrea Quarti, Marco Pozzi, Stefano Gasparini, Ines Carloni and Fernando Maria de Benedictis
    Citation: Italian Journal of Pediatrics 2014 40:18
  46. The editors of Italian Journal of Pediatrics would like to thank all our reviewers who have contributed to the journal in Volume 39 (2013).

    Authors: Sergio Bernasconi, Carlo Caffarelli and Francesca Santamaria
    Citation: Italian Journal of Pediatrics 2014 40:15

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