Critical Care

This section considers studies regarding all aspects of practice and research in critical care within the context of children and adolescents.

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  1. Case report

    NBAS mutations cause acute liver failure: when acetaminophen is not a culprit

    Pediatric acute-liver-failure due to acetaminophen (APAP) administration at therapeutic dosage is rare, while viral infections and metabolic defects are the prevalent causes. Yet, as acetaminophen is routinely...

    Pier Luigi Calvo, Francesco Tandoi, Tobias B. Haak, Andrea Brunati, Michele Pinon, Dominic Dell Olio, Renato Romagnoli and Marco Spada

    Italian Journal of Pediatrics 2017 43:88

    Published on: 25 September 2017

  2. Case report

    Management and long-term evolution of a patient with 3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency

    3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase deficiency is a rare inborn error of metabolism characterized by recurrent metabolic crises caused by fasting, intercurrent illness and excessive physical ...

    Juan Ignacio Muñoz-Bonet, María del Carmen Ortega-Sánchez and José Luis León Guijarro

    Italian Journal of Pediatrics 2017 43:12

    Published on: 19 January 2017

  3. Research

    Performances of low level hospital health caregivers after a neonatal resuscitation course

    High fidelity simulation has been executed to allow the evaluation of technical and non-technical skills of health caregivers. Our objective was to assess technical and non-technical performances of low level ...

    Giuseppe De Bernardo, Desirée Sordino, Francesco Cavallin, Veronica Mardegan, Nicoletta Doglioni, Maria Luisa Tataranno and Daniele Trevisanuto

    Italian Journal of Pediatrics 2016 42:100

    Published on: 18 November 2016

  4. Research

    Diagnostic value of soluble triggering receptor expressed on myeloid cells in paediatric sepsis: a systematic review

    Differential diagnosis between sepsis and non-infectious inflammatory disorders demands improved biomarkers. Soluble Triggering Receptor Expression on Myeloid cells (sTREM-1) is an activating receptor whose ro...

    Giuseppe Pontrelli, Franco De Crescenzo, Roberto Buzzetti, Francesca Calò Carducci, Alessandro Jenkner, Donato Amodio, Maia De Luca, Sara Chiurchiù, Elin Haf Davies, Alessandra Simonetti, Elena Ferretti, Martina Della Corte, Luca Gramatica, Susanna Livadiotti and Paolo Rossi

    Italian Journal of Pediatrics 2016 42:44

    Published on: 27 April 2016

  5. Case report

    Antithrombotic prophylaxis in a patient with nephrotic syndrome and congenital protein S deficiency

    Nephrotic syndrome confers an acquired prothrombotic phenotype due to the urinary loss of anticoagulant proteins.Patients with reactivation of nephrotic syndrome may develop thrombosis.

    Andrea Artoni, Serena Maria Passamonti, Alberto Edefonti, Francesca Gianniello, Vittorio Civelli and Ida Martinelli

    Italian Journal of Pediatrics 2016 42:22

    Published on: 29 February 2016

  6. Research

    Acetaminophen administration in pediatric age: an observational prospective cross-sectional study

    Parents often do not consider fever as an important physiological response and mechanism of defense against infections that leads to inappropriate use of antipyretics and potentially dangerous side effects. Th...

    Riccardo Lubrano, Sara Paoli, Marco Bonci, Luigi Di Ruzza, Corrado Cecchetti, Raffaele Falsaperla, Piero Pavone, Nassim Matin, Giovanna Vitaliti and Isotta Gentile

    Italian Journal of Pediatrics 2016 42:20

    Published on: 26 February 2016

  7. Case report

    Vacuum assisted closure for the treatment of complex wounds and enterocutaneous fistulas in full term and premature neonates: a case report

    The Vacuum Assisted Closure (VAC) system has become an effective treatment for acute and chronic wound defects. Although its use has been reported in wound care of children and premature infants, the managemen...

    Filomena Valentina Paradiso, Lorenzo Nanni, Laura Merli, Erika Adalgisa De Marco, Vincenzo Davide Catania, Alessandra Taddei, Carlo Manzoni and Giorgio Conti

    Italian Journal of Pediatrics 2016 42:2

    Published on: 11 January 2016

  8. Research

    “Risk factors of birth asphyxia”

    Birth asphyxia is an insult to the fetus or newborn due to failure to breath or breathing poorly, leads to decrease oxygen perfusion to various organs. According to WHO, 4 million neonatal deaths occurred each...

    Hafiz Muhammad Aslam, Shafaq Saleem, Rafia Afzal, Umair Iqbal, Sehrish Muhammad Saleem, Muhammad Waqas Abid Shaikh and Nazish Shahid

    Italian Journal of Pediatrics 2014 40:94

    Published on: 20 December 2014

  9. Research

    Childhood intussusceptions at a tertiary care hospital in northwestern Tanzania: a diagnostic and therapeutic challenge in resource-limited setting

    Intussusception remains a common cause of bowel obstruction in children and results in significant morbidity and mortality if not promptly treated. There is a paucity of prospective studies regarding childhood...

    Phillipo L Chalya, Neema M Kayange and Alphonce B Chandika

    Italian Journal of Pediatrics 2014 40:28

    Published on: 11 March 2014

  10. Case report

    Kawasaki disease in a girl with turner syndrome: a remarkable association

    We describe a girl with Turner syndrome, a genetic disorder of the X chromosome in a phenotypic female at increased risk of autoimmune and immunological diseases, who developed Kawasaki disease at the age of f...

    Stefano Stagi, Stefania Losi, Francesco Chiarelli, Maurizio de Martino and Fernanda Falcini

    Italian Journal of Pediatrics 2014 40:24

    Published on: 28 February 2014

  11. Review

    Doing without codeine: why and what are the alternatives?

    Codeine is a mild opioid widely used as an analgesic in various age groups, including various pediatric settings. It is a prodrug that owes its analgesic effect almost entirely to the principal metabolite: mor...

    Franca Benini and Egidio Barbi

    Italian Journal of Pediatrics 2014 40:16

    Published on: 11 February 2014

  12. Research

    Empirical examination of the indicator ‘pediatric gastroenteritis hospitalization rate’ based on administrative hospital data in Italy

    Awareness of the importance of strengthening investments in child health and monitoring the quality of services in the pediatric field is increasing. The Pediatric Quality Indicators developed by the US Agency...

    Jacopo Lenzi, Lorenza Luciano, Kathryn Mack McDonald, Simona Rosa, Gianfranco Damiani, Giovanni Corsello and Maria Pia Fantini

    Italian Journal of Pediatrics 2014 40:14

    Published on: 11 February 2014

  13. Research

    Empirical validation of the “Pediatric Asthma Hospitalization Rate” indicator

    Quality assessment in pediatric care has recently gained momentum. Although many of the approaches to indicator development are similar regardless of the population of interest, few nationwide sets of indicato...

    Lorenza Luciano, Jacopo Lenzi, Kathryn Mack McDonald, Simona Rosa, Gianfranco Damiani, Giovanni Corsello and Maria Pia Fantini

    Italian Journal of Pediatrics 2014 40:7

    Published on: 21 January 2014

  14. Research

    Application of a score system to evaluate the risk of malnutrition in a multiple hospital setting

    An increased but unpredictable risk of malnutrition is associated with hospitalization, especially in children with chronic diseases. We investigated the applicability of Screening Tool for Risk of Impaired Nu...

    Maria Immacolata Spagnuolo, Ilaria Liguoro, Fabrizia Chiatto, Daniela Mambretti and Alfredo Guarino

    Italian Journal of Pediatrics 2013 39:81

    Published on: 27 December 2013

  15. Research

    Association between radiological findings and severity of community-acquired pneumonia in children

    There are few published data concerning radiological findings and their relationship with community-acquired pneumonia (CAP) severity. The aim if this study was to assess radiographic findings in children with...

    Maria Francesca Patria, Benedetta Longhi, Mara Lelii, Carlotta Galeone, Maria Angela Pavesi and Susanna Esposito

    Italian Journal of Pediatrics 2013 39:56

    Published on: 13 September 2013

  16. Research

    Evaluation of neutrophil gelatinase-associated lipocalin in pediatric patients with acute rotavirus gastroenteritis and dehydration

    Dehydration caused by acute rotavirus gastroenteritis is a frequent finding in pediatric patients. The most important treatment modality in these patients is recognising and treating dehydration, electrolyte i...

    Tanju Çelik, Emel Altekin, Rana İşgüder, Yasin Kenesari, Murat Duman and Nur Arslan

    Italian Journal of Pediatrics 2013 39:52

    Published on: 3 September 2013

  17. Research

    Should a hospitalized child receive empiric treatment with acyclovir?

    Herpes simplex encephalitis is associated with substantial morbidity and mortality and may be related to timely diagnosis and treatment. While awaiting the results of testing, hospitalization and empiric treat...

    Dina M Kulik, Magda Mekky, Ming Yang, Ari Bitnun and Patricia C Parkin

    Italian Journal of Pediatrics 2012 38:72

    Published on: 17 December 2012

  18. Case report

    Unusual osseous presentation of blastomycosis in an immigrant child: a challenge for European pediatricians

    Blastomycosis, caused by the thermally dimorphic fungus Blastomyces dermatitidis is a systemic pyogranulomatous infection, endemic in United States and Canada, with few reported cases in Africa and Asia. It is...

    Margherita Codifava, Azzurra Guerra, Giulio Rossi, Paolo Paolucci and Lorenzo Iughetti

    Italian Journal of Pediatrics 2012 38:69

    Published on: 10 December 2012

  19. Case report

    Adams-Stokes attack as the first symptom of acute rheumatic fever: report of an adolescent case and review of the literature

    Acquired complete heart block, in pediatric age is mainly the results of direct injury to conduction tissue during cardiac surgery or cardiac catheterisation. It can also be observed in different clinical sett...

    Nicola Carano, Ilaria Bo, Bertrand Tchana, Erica Vecchione, Silvia Fantoni and Aldo Agnetti

    Italian Journal of Pediatrics 2012 38:61

    Published on: 30 October 2012

  20. Case report

    Acute adrenal failure as the presenting feature of primary antiphospholipid syndrome in a child

    Antiphospholipid syndrome (APS) is characterized by recurrent arterial and venous thrombosis and detection of antiphospholipid antibodies (aPLs). This syndrome may be associated with connective tissue disorder...

    Nicola Improda, Maria Alessio, Donatella Capalbo, Giustina Russo, Ida D’Acunzo, Loredana Palamaro, Claudio Pignata and Mariacarolina Salerno

    Italian Journal of Pediatrics 2012 38:49

    Published on: 20 September 2012

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Società Italiana di Pediatria

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