Allergology and Immunology

This section considers studies regarding the epidemiology, pathology, prevention, and control of allergic and immunologic diseases in children and adolescents.

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  1. Review

    ANCA-associated vasculitis in childhood: recent advances

    Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides are rare systemic diseases that usually occur in adulthood. They comprise granulomatosis with polyangiitis (GPA, Wegener’s), microscopic poly...

    Marta Calatroni, Elena Oliva, Davide Gianfreda, Gina Gregorini, Marco Allinovi, Giuseppe A. Ramirez, Enrica P. Bozzolo, Sara Monti, Claudia Bracaglia, Giulia Marucci, Monica Bodria, Renato A. Sinico, Federico Pieruzzi, Gabriella Moroni, Serena Pastore, Giacomo Emmi…

    Italian Journal of Pediatrics 2017 43:46

    Published on: 5 May 2017

  2. Letter to the Editor

    The utility of the basophil activation test in the diagnosis of immediate amoxicillin or amoxicillin-clavulanate hypersensitivity in children and adults

    The basophil activation test (BAT), has been proposed as a possible assay for the diagnosis of immediate-type allergy to beta-lactams (BLs).

    Simona Barni, Francesca Mori, Claudia Valleriani, Giusi Mangone, Sergio Testi, Francesca Saretta, Lucrezia Sarti, Neri Pucci, Maurizio de Martino, Chiara Azzari and Elio Novembre

    Italian Journal of Pediatrics 2017 43:42

    Published on: 21 April 2017

  3. Research

    Bifidobacterium mixture (B longum BB536, B infantis M-63, B breve M-16V) treatment in children with seasonal allergic rhinitis and intermittent asthma

    Allergic rhinitis (AR) and allergic asthma are caused by an IgE-mediated inflammatory reaction. Probiotics may exert anti-inflammatory and immune-modulatory activity. Thus, this study aimed at investigating wh...

    Michele Miraglia Del Giudice, Cristiana Indolfi, Michele Capasso, Nunzia Maiello, Fabio Decimo and Giorgio Ciprandi

    Italian Journal of Pediatrics 2017 43:25

    Published on: 7 March 2017

  4. Review

    Clinical practice recommendations for allergen-specific immunotherapy in children: the Italian consensus report

    Allergen-specific immunotherapy (AIT) is currently recognized as a clinically effective treatment for allergic diseases, with a unique disease-modifying effect. AIT was introduced in clinical practice one cent...

    Giovanni Battista Pajno, Roberto Bernardini, Diego Peroni, Stefania Arasi, Alberto Martelli, Massimo Landi, Giovanni Passalacqua, Antonella Muraro, Stefania La Grutta, Alessandro Fiocchi, Luciana Indinnimeo, Carlo Caffarelli, Elisabetta Calamelli, Pasquale Comberiati and Marzia Duse

    Italian Journal of Pediatrics 2017 43:13

    Published on: 23 January 2017

  5. Research

    Vitamin D deficiency and its impact on asthma severity in asthmatic children

    Despite obtaining evidences on association between vitamin D and development of lung in fetus, little is known about vitamin D level and its impact on severity of asthma in children. The present study aimed to...

    Nasrin Esfandiar, Fariba Alaei, Shahrzad Fallah, Delara Babaie and Niloofar Sedghi

    Italian Journal of Pediatrics 2016 42:108

    Published on: 17 December 2016

  6. Case report

    Eosinophilic esophagitis after congenital diaphragmatic hernia

    Eosinophilic esophagitis (EoE) is an increasingly diagnosed disease, especially in the western world. Although its pathogenesis remains poorly understood, there is strong evidence that the eosinophilic inflamm...

    Amelia Licari, Riccardo Castagnoli and Gian Luigi Marseglia

    Italian Journal of Pediatrics 2016 42:96

    Published on: 8 November 2016

  7. Review

    Atopy and autoimmune thyroid diseases: melatonin can be useful?

    Recently, there has been growing interest in the relationship between allergic and autoimmune diseases. Allergy and autoimmunity can be considered two potential outcomes of dysregulated immunity and analysis o...

    Gabriella D’Angelo, Lucia Marseglia, Sara Manti, Laura Colavita, Caterina Cuppari, Pietro Impellizzeri, Salvatore Arena, Teresa Arrigo, Carmelo Salpietro and Eloisa Gitto

    Italian Journal of Pediatrics 2016 42:95

    Published on: 4 November 2016

  8. Research

    Kawasaki disease in Sicily: clinical description and markers of disease severity

    Kawasaki disease (KD) is an acute systemic vasculitis of small and middle size arteries; 15-25 % of untreated patients and 5 % of patients treated with intravenous immunoglobulin (IVIG) develop coronary artery...

    Maria Cristina Maggio, Giovanni Corsello, Eugenia Prinzi and Rolando Cimaz

    Italian Journal of Pediatrics 2016 42:92

    Published on: 2 November 2016

  9. Case report

    Brain damage resembling acute necrotizing encephalopathy as a specific manifestation of haemophagocytic lymphohistiocytosis - induced by hypersensitivity

    Both haemophagocytic lymphohistiocytosis and acute necrotizing encephalopathy are life-threatening condition. It presents major diagnostic difficulties, since it may have a diversity in clinical picture and wi...

    Dongling Dai, Feiqiu Wen, Sixi Liu and Shaoming Zhou

    Italian Journal of Pediatrics 2016 42:79

    Published on: 31 August 2016

  10. Research

    The B-cell compartment in antibody-deficient infants and young children – developing common variable immunodeficiency or transient immune maturation?

    Hypogammaglobulinemia in early childhood is a common feature characterized by distinct intrinsic and extrinsic factors leading to disturbed peripheral blood lymphocyte homeostasis. Detailed flow cytometric imm...

    Aleksandra Szczawinska-Poplonyk, Katarzyna Tapolska-Jozwiak and Husam Samara

    Italian Journal of Pediatrics 2016 42:71

    Published on: 26 July 2016

  11. Research

    Shared genetic variants between serum levels of high-density lipoprotein cholesterol and wheezing in a cohort of children from Cyprus

    In a cohort of children in Cyprus, we recently reported low levels of high density lipoprotein cholesterol (HDL-C) to be associated with asthma. We examined whether genetic polymorphisms that were previously l...

    Panayiotis K. Yiallouros, Panayiotis Kouis, Ourania Kolokotroni, Sonia Youhanna, Savvas C. Savva, Kleanthi Dima, Aikaterini Zerva, Danielle Platt, Nicos Middleton and Pierre Zalloua

    Italian Journal of Pediatrics 2016 42:67

    Published on: 13 July 2016

  12. Case report

    Pulmonary manifestation of immunoglobulin G4-related disease in a 7-year-old immunodeficient boy with Epstein-Barr virus infection: a case report

    Immunoglobulin G4-related disease (IgG4-RD) is a multiorgan fibroinflammatory condition with lymphoplasmacytic infiltrates containing abundant IgG4-positive plasma cells. The immunopathogenesis of the disease ...

    Aleksandra Szczawinska-Poplonyk, Irena Wojsyk-Banaszak, Katarzyna Jonczyk-Potoczna and Anna Breborowicz

    Italian Journal of Pediatrics 2016 42:58

    Published on: 8 June 2016

  13. Commentary

    Beyond the “Choosing wisely”: a possible attempt

    Since the fundamental principles of the medical profession were clearly defined in a physician charter in 2002, special considerations have been expressed about the adequate distribution of health care resourc...

    Roberto Bernardini, Giampaolo Ricci, Francesca Cipriani, Flavio Civitelli, Luciana Indinnimeo, Domenico Minasi, Luigi Terracciano and Marzia Duse

    Italian Journal of Pediatrics 2016 42:55

    Published on: 28 May 2016

  14. Case report

    Omalizumab therapy in a 13-year-old boy with severe persistent asthma and concomitant eosinophilic esophagitis

    Eosinophilic esophagitis (EoE) has been defined as “asthma of the esophagus” for the large number of similarities between the two diseases. Omalizumab is an anti-Immunoglobulin E (IgE) antibody currently appro...

    Stefania Arasi, Stefano Costa, Giuseppe Magazzù, Antonio Ieni, Giuseppe Crisafulli, Lucia Caminiti, Fernanda Chiera, Mario Vaccaro, Michele Miraglia Del Giudice and Giovanni Battista Pajno

    Italian Journal of Pediatrics 2016 42:32

    Published on: 22 March 2016

  15. Review

    Consensus Conference on Clinical Management of pediatric Atopic Dermatitis

    The Italian Consensus Conference on clinical management of atopic dermatitis in children reflects the best and most recent scientific evidence, with the aim to provide specialists with a useful tool for managi...

    Elena Galli, Iria Neri, Giampaolo Ricci, Ermanno Baldo, Maurizio Barone, Anna Belloni Fortina, Roberto Bernardini, Irene Berti, Carlo Caffarelli, Elisabetta Calamelli, Lucetta Capra, Rossella Carello, Francesca Cipriani, Pasquale Comberiati, Andrea Diociaiuti, Maya El Hachem…

    Italian Journal of Pediatrics 2016 42:26

    Published on: 2 March 2016

  16. Research

    Severe asthma features in children: a case–control online survey

    Very few studies have explored the distinguishing features of severe asthma in childhood in Europe, and only one study was conducted in Southern Europe. The aim of this study was to provide a detailed characte...

    Silvia Montella, Eugenio Baraldi, Salvatore Cazzato, Raffaele Aralla, Mariangela Berardi, Luigia Maria Brunetti, Fabio Cardinale, Renato Cutrera, Fernando Maria de Benedictis, Emanuela di Palmo, Sabrina Di Pillo, Grazia Fenu, Stefania La Grutta, Enrico Lombardi, Giorgio Piacentini, Francesca Santamaria…

    Italian Journal of Pediatrics 2016 42:9

    Published on: 22 January 2016

  17. Research

    Sensitization pattern to inhalant and food allergens in symptomatic children at first evaluation

    Data on specific IgE sensitization prevalence in children with allergy-like symptoms seen in the primary care setting are rare. Early diagnosis of allergic diseases is important to prevent clinical manifestati...

    Alessandro Fiocchi, Valentina Pecora, Carl Johan Petersson, Lamia Dahdah, Magnus P. Borres, Maria J. Amengual, Johannes Huss-Marp, Oscar Mazzina and Francesco Di Girolamo

    Italian Journal of Pediatrics 2015 41:96

    Published on: 8 December 2015

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Società Italiana di Pediatria

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