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This section considers studies regarding the epidemiology, pathology, prevention, and control of allergic and immunologic diseases in children and adolescents.
Research
Data on specific IgE sensitization prevalence in children with allergy-like symptoms seen in the primary care setting are rare. Early diagnosis of allergic diseases is important to prevent clinical manifestati...
Italian Journal of Pediatrics 2015 41:96
Published on: 8 December 2015
Research
We aimed to evaluate the risk factors in preschool children admitted to inpatient services with a diagnosis of recurrent attacks of wheezing.
Italian Journal of Pediatrics 2015 41:91
Published on: 17 November 2015
Review
Celiac Disease (CD) is an immune-mediated systemic disorder elicited by gluten and related prolamines in genetically susceptible individuals and it is the result of the interaction between genetic and environm...
Italian Journal of Pediatrics 2015 41:57
Published on: 14 August 2015
Research
Food allergies are perceived as a significant problem in school environments; as a result, a teacher’s ability to recognise and deal with allergic reactions is of fundamental importance to protect children’s h...
Italian Journal of Pediatrics 2014 40:100
Published on: 4 December 2014
Research
Recurrent respiratory infections (RRI), such as the presence of at least one of the following criteria: i) >6 RI per year; ii) >1 RI per month involving upper airways from September to April; iii) >3 RI involv...
Italian Journal of Pediatrics 2014 40:93
Published on: 23 November 2014
Case report
Severe Congenital Neutropenia type 4 (SCN4, OMIM 612541) is a rare autosomal recessive disease due to mutations in the G6PC3 gene. The phenotype comprises neutropenia of variable severity and other anomalies incl...
Italian Journal of Pediatrics 2014 40:80
Published on: 14 November 2014
Case report
The syndrome of immune dysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) is a rare disorder caused by mutations in the FOXP3 gene. Diarrhea, diabetes and dermatitis are the hallmark of the diseas...
Italian Journal of Pediatrics 2014 40:68
Published on: 18 October 2014
Research
Atopic dermatitis (AD) is a chronic inflammatory skin disease and can be the first step of the atopic march.
Italian Journal of Pediatrics 2014 40:46
Published on: 12 May 2014
Research
During the last century, mass vaccination programs have achieved considerable success across the world in immunizing against several serious infectious diseases. However, vaccinations are threatened by their o...
Italian Journal of Pediatrics 2014 40:31
Published on: 31 March 2014
Research
The low uptake of tetanus vaccine and its resultant high burden of tetanus in Nigeria suggest the need to improve routine and booster vaccination in children and adolescents. However, epidemiological evidence ...
Italian Journal of Pediatrics 2014 40:29
Published on: 17 March 2014
Research
Asthma is the result of a complex interaction between environmental factors and genetic variants that confer susceptibility. The glutathione S-transferases (GSTT1 and GSTM1) are phase II enzymes thought to pro...
Italian Journal of Pediatrics 2014 40:22
Published on: 21 February 2014
Case report
Invasive aspergillosis is an important cause of morbidity and mortality in immunocompromised patients. Among primary immunodefiencies, chronic granulomatous disease (CGD) has the highest prevalence of invasive...
Italian Journal of Pediatrics 2014 40:2
Published on: 8 January 2014
Review
Although the guidelines on the diagnosis and treatment of food allergy recognize the role of nutrition, there is few literature on the practical issues concerning the nutritional management of children with fo...
Italian Journal of Pediatrics 2014 40:1
Published on: 3 January 2014
Commentary
The epidemic of childhood allergic disorders has been associated to the decline of infectious disease. However, exposure to many triggers (airborne viruses, tobacco smoke, pollution, indoor allergens, etc.) co...
Italian Journal of Pediatrics 2013 39:80
Published on: 27 December 2013
Research
Epidemiological studies show that vitamin D deficiency and insufficiency are common worldwide and associated with many diseases including asthma. Our aim was to evaluate vitamin D insufficiency and its clinica...
Italian Journal of Pediatrics 2013 39:78
Published on: 13 December 2013
Commentary
At the end of 1990s, acute respiratory tract infections (ARTIs) were called the 'forgotten pandemic’, with a clear dichotomy between developing and industrialised countries in mortality and morbidity, the main...
Italian Journal of Pediatrics 2013 39:75
Published on: 6 December 2013
Review
Melatonin, a versatile molecule, is synthesized by the pineal gland but also by other organs, including gastrointestinal tract, retina, thymus, bone marrow, and by leukocytes. Besides playing an important role...
Italian Journal of Pediatrics 2013 39:61
Published on: 3 October 2013
Case report
We report on pediatric patient with Nijmegen breakage syndrome (NBS), a rare DNA repair disorder characterized by microcephaly, immunodeficiency and predisposition to malignant lymphomas, who developed juvenil...
Italian Journal of Pediatrics 2013 39:59
Published on: 17 September 2013
Case report
Severe Combined Immunodeficiency (SCID) is one of the most severe forms of primary immunodeficiency (PID). Complications of BCG vaccination, especially disseminated infection and its most severe forms, are kno...
Italian Journal of Pediatrics 2013 39:54
Published on: 10 September 2013
Review
Skin prick tests are the first investigation in allergy diagnostics and their use is described in all the guidelines on atopic eczema. However, the clinical usefulness of skin prick tests is the subject of gre...
Italian Journal of Pediatrics 2013 39:48
Published on: 31 July 2013
