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Neonatology and Fetal Medicine

This section covers all aspects of neonatal and fetal health, disease, treatment, and outcomes.

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  1. To determine longitudinally the relationship between serum 25-hydroxyvitamin D (vitamin D) and vitamin D-binding protein (DBP) levels in mother-neonate pairs and evaluate the efficiency of prophylactic vitamin...

    Authors: Hakan Doneray, Remziye Seda Yesilcibik, Esra Laloglu, Metin Ingec and Zerrin Orbak

    Citation: Italian Journal of Pediatrics 2018 44:15

    Content type: Research

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  2. Acute bronchiolitis is the most common cause of hospitalizations in infants < 12 months of age and preventive efforts remain the most important strategy to date. Recently prophylaxis with palivizumab (PLV) was...

    Authors: Simonetta Picone, Adele Fabiano, Davide Roma and Piermichele Paolillo

    Citation: Italian Journal of Pediatrics 2018 44:11

    Content type: Letter to the Editor

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  3. Perinatal asphyxia (PA) occurs in about 2 to 10 per 1000 live full-term births. Although neonatal epileptic seizures are observed in up to 60% of cases, PA may mimic or subtend other conditions. Hypoxia relate...

    Authors: Giacomo Biasucci, Nicola Morelli, Federica Natacci and Massimo Mastrangelo

    Citation: Italian Journal of Pediatrics 2018 44:8

    Content type: Case report

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  4. In Neonatal Intensive Care Units (NICUs), parent satisfaction and their experiences are fundamental to assess clinical practice and improve the quality of care delivered to infants and parents. Recently, a spe...

    Authors: Immacolata Dall’Oglio, Martina Fiori, Emanuela Tiozzo, Rachele Mascolo, Anna Portanova, Orsola Gawronski, Angela Ragni, Patrizia Amadio, Antonello Cocchieri, Roberta Fida, Rosaria Alvaro, Gennaro Rocco and Jos M. Latour

    Citation: Italian Journal of Pediatrics 2018 44:5

    Content type: Research

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  5. In neonatal endotracheal intubation, excessive pressure on soft tissues during laryngoscopy can determine permanent injury. Low-fidelity skill trainers do not give valid feedback about this issue. This study d...

    Authors: Davide Panizza, Rosa T. Scaramuzzo, Francesca Moscuzza, Ilaria Vannozzi, Massimiliano Ciantelli, Marzia Gentile, Ilaria Baldoli, Selene Tognarelli, Antonio Boldrini and Armando Cuttano

    Citation: Italian Journal of Pediatrics 2018 44:4

    Content type: Research

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  6. Pulmonary disorders and respiratory failure represent one of the most common morbidities of preterm newborns admitted to neonatal intensive care units (NICUs). The use of nasal high-flow therapy (nHFT) has bee...

    Authors: Antonio Di Mauro, Manuela Capozza, Sergio Cotugno, Silvio Tafuri, Francesco Paolo Bianchi, Federico Schettini, Raffaella Panza and Nicola Laforgia

    Citation: Italian Journal of Pediatrics 2017 43:116

    Content type: Research

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  7. Despite an increased use of non-invasive ventilatory strategies and gentle ventilation, pneumothorax remains a common complication in preterm infants. The ventilator management of infants with air leaks remain...

    Authors: Claudia Aurilia, Cinzia Ricci, Milena Tana, Chiara Tirone, Alessandra Lio, Alessandro Gambacorta, Angela Paladini and Giovanni Vento

    Citation: Italian Journal of Pediatrics 2017 43:114

    Content type: Case report

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  8. The rapid advancement of next-generation sequencing (NGS) technology and the decrease in costs for whole-exome sequencing (WES) and whole-genome sequening (WGS), has prompted its clinical application in severa...

    Authors: Alessandro Borghesi, Maria Antonietta Mencarelli, Luigi Memo, Giovanni Battista Ferrero, Andrea Bartuli, Maurizio Genuardi, Mauro Stronati, Alberto Villani, Alessandra Renieri and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2017 43:100

    Content type: Review

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  9. There are no Italian data regarding the strategies for preventing neonatal group B streptococcal (GBS) infection. We conducted a national survey in order to explore obstetrical, neonatal and microbiological pr...

    Authors: Chryssoula Tzialla, Alberto Berardi, Claudio Farina, Pierangelo Clerici, Alessandro Borghesi, Elsa Viora, Paolo Scollo and Mauro Stronati

    Citation: Italian Journal of Pediatrics 2017 43:98

    Content type: Research

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  10. The relationship between premature birth and early cognitive function as measured by eye-tracking data remains unexplored. The aim of this study was to determine the effect of prematurity on the development of...

    Authors: Hokyoung Ryu, Garam Han, Jaeran Choi, Hyun-Kyung Park, Mi Jung Kim, Dong-Hyun Ahn and Hyun Ju Lee

    Citation: Italian Journal of Pediatrics 2017 43:90

    Content type: Research

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  11. Newborn hearing screening has to be considered the first step of a program for the identification, diagnosis, treatment and habilitation/rehabilitation of children with hearing impairment.

    Authors: Stefano Berrettini, Paolo Ghirri, Francesco Lazzerini, Giovanni Lenzi and Francesca Forli

    Citation: Italian Journal of Pediatrics 2017 43:82

    Content type: Commentary

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  12. The Mediterranean diet has been for a very long time the basis of food habits all over the countries of the Mediterranean basin, originally founded on rural models and low consumption of meat products and high...

    Authors: Maximilian Fischer, Mauro Stronati and Marcello Lanari

    Citation: Italian Journal of Pediatrics 2017 43:74

    Content type: Review

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  13. Following the most recent modification by the American Academy of Pediatrics, based on American studies on RSV epidemiology, the Italian Drug Agency (AIFA) decided to limit the total financial coverage of the ...

    Authors: Antonino Capizzi, Michela Silvestri, Andrea Orsi, Renato Cutrera, Giovanni A. Rossi and Oliviero Sacco

    Citation: Italian Journal of Pediatrics 2017 43:71

    Content type: Letter to the Editor

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  14. The recognition, follow-up, and early treatment of neonatal jaundice has become more difficult, since the earlier discharge of newborns from hospitals has become common practice. Since intrapartum hypoxic stre...

    Authors: Vincenzo Zanardo, Federico de Luca, Alphonse K. Simbi, Matteo Parotto, Pietro Guerrini and Gianluca Straface

    Citation: Italian Journal of Pediatrics 2017 43:67

    Content type: Research

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  15. In Cameroon, sustainable effort needs to be done to reduce the current neonatal mortality rate from 21 deaths per 1000 live births to the global target of fewer than ten deaths per 1000 live births by 2035. We...

    Authors: Paul Koki Ndombo, Quinta Mua Ekei, Joel Noutakdie Tochie, Mazou Ngou Temgoua, Francky Teddy Endomba Angong, Ferdinand Ndom Ntock and Lawrence Mbuagbaw

    Citation: Italian Journal of Pediatrics 2017 43:52

    Content type: Research

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  16. Recently, the prevalence of chromosomal abnormalities (CA) increased as the increasing proportion of mothers with advanced age. We aimed to explore the prevalence of CA in relation to maternal age and perinata...

    Authors: Xiao-Hui Zhang, Li-Qian Qiu, Ying-Hui Ye and Jian Xu

    Citation: Italian Journal of Pediatrics 2017 43:47

    Content type: Research

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  19. Drug use in preterm neonates admitted to Neonatal Intensive Care Unit (NICU) has been investigated, so far, in terms of unauthorized or off-label use; very little is known on the use of combinations of differe...

    Authors: A. Girardi, S. Galletti, E. Raschi, A. Koci, E. Poluzzi, G. Faldella and F. De Ponti

    Citation: Italian Journal of Pediatrics 2017 43:37

    Content type: Research

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  20. Family-Centred Care (FCC) is recognized as an important component of all paediatric care, including neonatal care, although practical clinical guidelines to support this care model are still needed in Italy. T...

    Authors: Giuseppe De Bernardo, Maria Svelto, Maurizio Giordano, Desiree Sordino and Marina Riccitelli

    Citation: Italian Journal of Pediatrics 2017 43:36

    Content type: Research

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  21. We studied late preterm and term infants who were admitted to our neonatal care unit in a tertiary hospital for unexpected episodes of cyanosis that occurred during rooming-in for evaluation of their frequency...

    Authors: Carlo Dani, Livia Drovandi, Giovanna Bertini, Chiara Poggi and Simone Pratesi

    Citation: Italian Journal of Pediatrics 2017 43:35

    Content type: Research

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  22. We aimed to examine current bedside analgesia/sedation (A/S) and pain assessment (PA) practices in Italian neonatal intensive care units (NICUs) in relation to the findings of an epidemiological European study...

    Authors: Paola Lago, Anna Chiara Frigo, Eugenio Baraldi, Roberta Pozzato, Emilie Courtois, Jérôme Rambaud, Kanwaljeet J. S. Anand and Ricardo Carbajal

    Citation: Italian Journal of Pediatrics 2017 43:26

    Content type: Research

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  23. Guidelines on immunoprophylaxis for prevention of RSV infection recommend it in preterm babies born before 29 wGA; in babies affected by bronchopulmonary dysplasia or congenital heart defects; and in post-hear...

    Authors: Gianvincenzo Zuccotti and Valentina Fabiano

    Citation: Italian Journal of Pediatrics 2017 43:17

    Content type: Letter to the Editor

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  24. Candida parapsilosis is increasingly responsible for invasive candidiasis in neonates. This study investigates phenotypic and genotypic features of C. parapsilosis microbial isolates a...

    Authors: Carmine Garzillo, Maria Bagattini, Lidija Bogdanović, Anna Di Popolo, Vita Dora Iula, Maria Rosaria Catania, Francesco Raimondi, Maria Triassi and Raffaele Zarrilli

    Citation: Italian Journal of Pediatrics 2017 43:10

    Content type: Research

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  26. Cytomegalovirus is the most common cause of congenital infection in the developed countries. Gastrointestinal involvement has been extensively described in both adult and paediatric immunocompromised patients ...

    Authors: Claudia Colomba, Mario Giuffrè, Simona La Placa, Antonio Cascio, Marcello Trizzino, Simona De Grazia and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2016 42:105

    Content type: Case report

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  27. White matter (WM) abnormalities associated with prematurity are one of the most important causes of neurological disability that involves spastic motor deficits in preterm newborns. This study aimed to evaluat...

    Authors: Do-yeon Kim, Hyun-Kyung Park, Nam-Su Kim, Se-Jin Hwang and Hyun Ju Lee

    Citation: Italian Journal of Pediatrics 2016 42:104

    Content type: Research

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  28. Infants born at 34 to 36 weeks of gestation (late preterm) are at greater risk for adverse outcomes than those born at 37 weeks of gestation or later. Aim of this paper is to examine risk factors for late pret...

    Authors: M. P. De Carolis, G. Pinna, C. Cocca, S. A. Rubortone, C. Romagnoli, I. Bersani, S. Salvi, A. Lanzone and S. De Carolis

    Citation: Italian Journal of Pediatrics 2016 42:87

    Content type: Research

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  31. To compare cost effectiveness of ‘Kangaroo Ward Care’ with ‘Intermediate Intensive Care’ in stable very low birth weight infants (birth weight < 1100 g).

    Authors: Deepak Sharma, Srinivas Murki and Tejo Pratap Oleti

    Citation: Italian Journal of Pediatrics 2016 42:64

    Content type: Research

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  33. We assessed the incidence of infants born small-for-gestational-age (SGA) and large-for-gestational-age (LGA) in an Italian cohort over 20 years (1993–2013). Furthermore, we investigated maternal factors assoc...

    Authors: Valentina Chiavaroli, Valeria Castorani, Paola Guidone, José G. B. Derraik, Marco Liberati, Francesco Chiarelli and Angelika Mohn

    Citation: Italian Journal of Pediatrics 2016 42:42

    Content type: Research

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  34. The most widespread method for the treatment of donor milk is the Holder pasteurization (HoP). The available literature data show that HoP may cause degradation of some bioactive components. The aim of this st...

    Authors: Chiara Peila, Alessandra Coscia, Enrico Bertino, Maria Cavaletto, Stefano Spertino, Sara Icardi, Claudia Tortone, Gerard H. A. Visser and Diego Gazzolo

    Citation: Italian Journal of Pediatrics 2016 42:36

    Content type: Research

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  35. Neonatal units’ volume of activity, and other quantitative and qualitative variables, such as staffing, workload, work environment, care organization and geographical location, may influence the outcome of hig...

    Authors: Carlo Corchia, Simone Fanelli, Luigi Gagliardi, Roberto Bellù, Antonello Zangrandi, Anna Persico and Rinaldo Zanini

    Citation: Italian Journal of Pediatrics 2016 42:34

    Content type: Research

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  36. Continuous glucose monitoring using subcutaneous sensors has been validated in adults and children with diabetes, and was found to be useful in the management of glucose control. We aimed to assess feasibility...

    Authors: Eloisa Tiberi, Francesco Cota, Giovanni Barone, Alessandro Perri, Valerio Romano, Rossella Iannotta, Costantino Romagnoli and Enrico Zecca

    Citation: Italian Journal of Pediatrics 2016 42:29

    Content type: Research

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  38. Congenital hearing loss is the most frequent birth defect. The American Academy of Pediatrics and the Joint Committee on Infant Hearing established quality of care process indicators for Universal Newborn Hear...

    Authors: Carlo Giacomo Leo, Pierpaolo Mincarone, Saverio Sabina, Giuseppe Latini and John B. Wong

    Citation: Italian Journal of Pediatrics 2016 42:15

    Content type: Debate

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  39. To explore the association between maternal alcohol consumption and/or binge drinking and congenital heart defects (CHDs), we conducted a meta-analysis for more sufficient evidence on this issue.

    Authors: Zhongyuan Wen, Di Yu, Weiyan Zhang, Changfeng Fan, Liang Hu, Yu Feng, Lei Yang, Zeyu Wu, Runsen Chen, Ke-jie Yin and Xuming Mo

    Citation: Italian Journal of Pediatrics 2016 42:12

    Content type: Review

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  40. In addition to surfactant deficiency, increase of lung fluid content and secretion of fluid derived from the blood participate in the pathogenesis of RDS in newborns.

    Authors: Masoud Dehdashtian, Arash Malakian, Mohammad Reza Aramesh, Ali Mazori, Mohammad Hasan Aletayeb, Afsaneh Shirani and Shiva Bashirnejad

    Citation: Italian Journal of Pediatrics 2016 42:6

    Content type: Research

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  41. Neonatal Lupus Erythematosus (NLE) is an uncommon autoimmune disease characterized by cutaneous, hepatic, hematological, neurological and cardiac involvement.

    Authors: Francesco Savino, Serena Viola, Valentina Tarasco, Emanuela Locatelli, Alberto Ricagni and Paola Coppo

    Citation: Italian Journal of Pediatrics 2016 42:1

    Content type: Case report

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  42. Respiratory Syncytial Virus infections are one of the leading causes of severe respiratory diseases that require hospitalization and, in some cases, intensive care. Once resolved, there may be respiratory sequ...

    Authors: Lina Bollani, Eugenio Baraldi, Gaetano Chirico, Andrea Dotta, Marcello Lanari, Antonello Del Vecchio, Paolo Manzoni, Antonio Boldrini, Piermichele Paolillo, Sandra Di Fabio, Luigi Orfeo, Mauro Stronati and Costantino Romagnoli

    Citation: Italian Journal of Pediatrics 2015 41:97

    Content type: Review

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  43. Infant massage is a natural way for caregivers to improve health, sleep patterns, and reduce colic. We aimed to investigate the effects of infant massage on neonates with jaundice who are also receiving photot...

    Authors: Chien-Heng Lin, Hsiu-Chuan Yang, Chien-Sheng Cheng and Chin-En Yen

    Citation: Italian Journal of Pediatrics 2015 41:94

    Content type: Research

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  44. Necrotizing enterocolitis (NEC) affects predominantly preterm infants, who have specific risk factors leading to intestinal dysbiosis. Manipulations of gut microbiota through probiotics have the potential to prev...

    Authors: Arianna Aceti, Davide Gori, Giovanni Barone, Maria Luisa Callegari, Antonio Di Mauro, Maria Pia Fantini, Flavia Indrio, Luca Maggio, Fabio Meneghin, Lorenzo Morelli, Gianvincenzo Zuccotti and Luigi Corvaglia

    Citation: Italian Journal of Pediatrics 2015 41:89

    Content type: Review

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  45. Thymic enlargement is a common and physiological finding in children and neonates’ X-rays, but it is usually asymptomatic. Occasionally it can cause respiratory distress. In most cases the aetiology of this e...

    Authors: Giancarlo Gargano, Anna Lucia Paltrinieri, Claudio Gallo, Luciana Di Pancrazio, Maria Federica Roversi and Fabrizio Ferrari

    Citation: Italian Journal of Pediatrics 2015 41:88

    Content type: Case report

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  46. Fraser Syndrome is a rare, autosomal recessive syndrome. It’s characterized primarily by cryptophthalmos, syndactyly and urogenital malformation. Respiratory malformations are frequently present and not taken ...

    Authors: Giuseppe De Bernardo, Maurizio Giordano, Antonino Di Toro, Desiree Sordino and Daniele De Brasi

    Citation: Italian Journal of Pediatrics 2015 41:86

    Content type: Case Report

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  47. Neonates born with meconium stained amniotic fluid (MSAF) can develop feed intolerance during first few days of post -natal period. A randomized controlled trial was conducted with the objectives of to find ou...

    Authors: Lokraj Shah, Gauri Shankar Shah, Rupa Rajbhandari Singh, Hanoon Pokharel and Om Prakash Mishra

    Citation: Italian Journal of Pediatrics 2015 41:85

    Content type: Research

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  48. Down syndrome (DS) is one of the most common chromosomal abnormalities among newborns. In recent years advances in perinatal and neonatal care have improved chance of survival for the children with DS. The obj...

    Authors: Tatjana Glivetic, Urelija Rodin, Milan Milosevic, Diana Mayer, Boris Filipovic-Grcic and Maida Seferovic Saric

    Citation: Italian Journal of Pediatrics 2015 41:81

    Content type: Research

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  50. Therapeutic hypothermia (TH) has become standard care in newborns with moderate to severe hypoxic ischemic encephalopathy (HIE), and the 2 most commonly used methods are selective head cooling (SHC) and whole ...

    Authors: Yalçın Çelik, Aytuğ Atıcı, Selvi Gülaşı, Khatuna Makharoblıdze, Gülçin Eskandari, Mehmet Ali Sungur and Serin Akbayır

    Citation: Italian Journal of Pediatrics 2015 41:79

    Content type: Research

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