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Neonatology and Fetal Medicine

This section covers all aspects of neonatal and fetal health, disease, treatment, and outcomes.

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  1. Content type: Research

    Hyperbilirubinaemia is one of the most frequent problems in otherwise healthy newborn infants. Early discharge of the healthy newborn infants, particularly those in whom breastfeeding is not fully established,...

    Authors: Costantino Romagnoli, Giovanni Barone, Simone Pratesi, Francesco Raimondi, Letizia Capasso, Enrico Zecca and Carlo Dani

    Citation: Italian Journal of Pediatrics 2014 40:11

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  2. Content type: Commentary

    About 90,000 preterm infants or babies with birth defects are born in Italy every year, nearly 250 per day. These congenital conditions and their outcomes represent the most important burden of disease affecti...

    Authors: Carlo Corchia and Pierpaolo Mastroiacovo

    Citation: Italian Journal of Pediatrics 2013 39:68

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  3. Content type: Research

    To investigate the effectiveness of IgM-enriched immunoglobulins (IgM-eIVIG) in reducing short-term mortality of neonates with proven late-onset sepsis.

    Authors: Letizia Capasso, Angela Carla Borrelli, Claudia Parrella, Silvia Lama, Teresa Ferrara, Clara Coppola, Maria Rosaria Catania, Vita Dora Iula and Francesco Raimondi

    Citation: Italian Journal of Pediatrics 2013 39:63

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  4. Content type: Research

    To evaluate the association between the genetic polymorphism of the solute carrier organic anion transporter family member 1B1 (SLCO1B1, also known as organic anion transport polypeptide C) and hyperbilirubine...

    Authors: Jiebo Liu, Jun Long, Shaofang Zhang, Xiaoyan Fang and Yuyuan Luo

    Citation: Italian Journal of Pediatrics 2013 39:49

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  5. Content type: Research

    Transcutaneous bilirubinometry is widely used to predict hyperbilirubinemia by using several devices. The aim of this study was to compare the predictive ability of BiliCheck vs JM-103 in identifying neonates ...

    Authors: Costantino Romagnoli, Piero Catenazzi, Giovanni Barone, Lucia Giordano, Riccardo Riccardi, Antonio Alberto Zuppa and Enrico Zecca

    Citation: Italian Journal of Pediatrics 2013 39:46

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  6. Content type: Research

    VATER association was first described in 1972 by Quan and Smith as an acronym which identifies a non-random co-occurrence of Vertebral anomalies, Anal atresia, Tracheoesophageal fistula and/or Esophageal atres...

    Authors: Simona La Placa, Mario Giuffrè, Antonella Gangemi, Stefania Di Noto, Federico Matina, Federica Nociforo, Vincenzo Antona, Maria Rita Di Pace, Maria Piccione and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2013 39:45

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  7. Content type: Research

    This study aims to investigate the incidence and the relative risk factors of retinopathy of prematurity (ROP) and posterior-ROP (P-ROP): ROP in Zone I and posterior Zone II, as well as to analyze the occurren...

    Authors: Cesarina Borroni, Carla Carlevaro, Sabrina Morzenti, Elena De Ponti, Valentina Bozzetti, Vito Console, Salvatore Capobianco and Paolo E Tagliabue

    Citation: Italian Journal of Pediatrics 2013 39:43

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  8. Content type: Case report

    Methadone is commonly prescribed as a substitute for illicit opioids. Use of methadone during pregnancy is associated with neonatal abstinence syndrome (NAS), reduced head circumference as well as a slight inc...

    Authors: Francesca Tinelli, Alessandra Gamucci, Roberta Battini and Giovanni Cioni

    Citation: Italian Journal of Pediatrics 2013 39:40

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  9. Content type: Case report

    3-hydroxy-3-methylglutaric aciduria (OMIM 246450) is a rare autosomal recessive inborn of metabolism due to the deficiency of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase, an enzyme involved both in t...

    Authors: Francesca Santarelli, Michela Cassanello, Ausilia Enea, Francesca Poma, Valentina D'Onofrio, Giovanna Guala, Giangiacomo Garrone, Paola Puccinelli, Ubaldo Caruso, Francesco Porta and Marco Spada

    Citation: Italian Journal of Pediatrics 2013 39:33

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  10. Content type: Review

    Feeding small for gestational age (SGA) newborns is extremely challenging and the neonatologist should be brave and cautious at the same time. Although these babies have a high risk of milk intolerance and nec...

    Authors: Giovanni Barone, Luca Maggio, Annalisa Saracino, Alessandro Perri, Costantino Romagnoli and Enrico Zecca

    Citation: Italian Journal of Pediatrics 2013 39:28

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  11. Content type: Research

    Intrauterine growth restriction (IUGR) and small for gestational age (SGA) birth have been considered possible indicators of the presence of malformations. The aim of this study is to evaluate such relationshi...

    Authors: Giuseppe Puccio, Mario Giuffré, Maria Piccione, Ettore Piro, Grazia Rinaudo and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2013 39:23

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  12. Content type: Research

    Infant mortality is a key indicator of child and population health. The aim of this study is to analyse the trends in infant mortality rates (IMRs) and their components (neonatal mortality rates-NMRs and post-...

    Authors: Laura Dallolio, Jacopo Lenzi and Maria Pia Fantini

    Citation: Italian Journal of Pediatrics 2013 39:19

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  13. Content type: Research

    There are several studies that have shown an increased risk of premature birth and developmental abnormalities with in vitro fertilization (IVF); however, the data on preterm mortality and morbidity are limited.

    Authors: Gülcan Turker, Emek Doger, Ayşe Engin Arısoy, Ayla Günlemez and Ayşe Sevim Gökalp

    Citation: Italian Journal of Pediatrics 2013 39:17

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  14. Content type: Research

    Birth defects are defined as those conditions that are substantially determined before or during birth and which are recognizable in early life. They are an important cause of morbidity and mortality in infant...

    Authors: Mohammad Zeeshan Raza, Asfandyar Sheikh, Syed Salman Ahmed, Sajid Ali and Syed Mumtaz Ali Naqvi

    Citation: Italian Journal of Pediatrics 2012 38:68

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  15. Content type: Case report

    Neonatal testicular tumors are rare and should be considered in the differential diagnosis of newborn scrotal masses. Juvenile granulosa cell tumor (JGCT) accounts for about 5% of all prepubertal testis tumors...

    Authors: Anna Lavinia Bulotta, Francesco Molinaro, Rossella Angotti, Francesco Ferrara, Giovanni Di Maggio, Edoardo Bindi and Mario Messina

    Citation: Italian Journal of Pediatrics 2012 38:67

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  16. Content type: Case report

    Medium chain acyl CoA dehydrogenase deficiency (MCAD) is the most common inborn error of fatty acid oxidation. This condition may lead to cellular energy shortage and cause severe clinical events such as hypok...

    Authors: Cristina Lovera, Francesco Porta, Anna Caciotti, Serena Catarzi, Michela Cassanello, Ubaldo Caruso, Maria Rita Gallina, Amelia Morrone and Marco Spada

    Citation: Italian Journal of Pediatrics 2012 38:59

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  17. Content type: Research

    We aimed to evaluate thyroid functions and volumes and detect abnormalities in 80 neonates with Down syndrome.

    Authors: Dilek Sarici, Mustafa Ali Akin, Selim Kurtoglu, Tamer Gunes, Mehmet Adnan Ozturk and Mustafa Akcakus

    Citation: Italian Journal of Pediatrics 2012 38:44

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  18. Content type: Research

    Perinatal asphyxia leading to hypoxic-ischemic encephalopathy (HIE) is a common problem causing multi organ dysfunction including myocardial involvement which can affect the outcome.

    Authors: Jyoti Agrawal, Gauri S Shah, Prakash Poudel, Nirmal Baral, Ajay Agrawal and Om P Mishra

    Citation: Italian Journal of Pediatrics 2012 38:33

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  19. Content type: Review

    The Pierre Robin Sequence features were first described by Robin in 1923 and include micrognathia, glossoptosis and respiratory distress with an incidence estimated as 1:8,500 to 1:20,000 newborns. Upper airwa...

    Authors: Enrico Sesenna, Alice S Magri, Cinzia Magnani, Bruno C Brevi and Marilena L Anghinoni

    Citation: Italian Journal of Pediatrics 2012 38:7

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  20. Content type: Research

    Meconium abnormalities are characterized by a wide spectrum of severity, from the meconium plug syndrome to the complicated meconium ileus associated with cystic fibrosis. Meconium Related Ileus in absence of ...

    Authors: Valentina Filomena Paradiso, Vito Briganti, Lucia Oriolo, Riccardo Coletta and Alessandro Calisti

    Citation: Italian Journal of Pediatrics 2011 37:55

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  21. Content type: Letter to the Editor

    Intrauterine growth retardation refers to a rate of growth of a fetus that is less than normal for the growth potential of a fetus (for that particular gestational age). As one of the leading causes of perinat...

    Authors: Taimur Saleem, Nida Sajjad, Sanna Fatima, Nida Habib, Syed R Ali and Maqbool Qadir

    Citation: Italian Journal of Pediatrics 2011 37:41

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  22. Content type: Review

    The early identification of pre-lingual deafness is necessary to minimize the consequences of hearing impairment on the future communication skills of a baby. According to the most recent international guideli...

    Authors: Paolo Ghirri, Annalisa Liumbruno, Sara Lunardi, Francesca Forli, Antonio Boldrini, Angelo Baggiani and Stefano Berrettini

    Citation: Italian Journal of Pediatrics 2011 37:16

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  23. Content type: Case report

    Breastfeeding has a major impact on CMV epidemiology. Postnatal CMV reactivation's incidence during lactation is nearby the maternal seroprevalence. Although perinatal CMV infection has practically no conseque...

    Authors: Manuela Chiavarini, Patrizia Bragetti, Alessandra Sensini, Elio Cenci, Roberto Castronari, Marta J Rossi, Ambra Fantauzzi and Liliana Minelli

    Citation: Italian Journal of Pediatrics 2011 37:6

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  24. Content type: Research

    The study deals with the characteristics of temperament of preterm infants during their preschool age in order to not only investigate likely "difficult or problematic profiles", guided by impairments driven b...

    Authors: Giovanna Perricone and M Regina Morales

    Citation: Italian Journal of Pediatrics 2011 37:4

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  25. Content type: Research

    Infants born to diabetic women have certain distinctive characteristics, including large size and high morbidity risks. The neonatal mortality rate is over five times that of infants of non diabetic mothers an...

    Authors: Peace I Opara, Tamunopriye Jaja and Uche C Onubogu

    Citation: Italian Journal of Pediatrics 2010 36:77

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  26. Content type: Debate

    Assisted reproductive technology has made great progress during the last three decades. After the initial enthusiasm, many ethical, legal and social issues related to the application of these procedures began ...

    Authors: Antonio A Zuppa, Giovanni Alighieri, Piero Catenazzi, Antonio Scorrano and Costantino Romagnoli

    Citation: Italian Journal of Pediatrics 2010 36:74

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  27. Content type: Research

    Intrauterine growth restriction (IUGR) is associated with several medical complications before and after delivery. The aim of this study was to evaluate the concordance between the fetal ultrasonographic measu...

    Authors: Nadia Liotto, Tatjana Radaelli, Anna Orsi, Emanuela Taricco, Paola Roggero, Maria L Giannì, Dario Consonni, Fabio Mosca and Irene Cetin

    Citation: Italian Journal of Pediatrics 2010 36:70

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  28. Content type: Research

    In neonatology the role of chest physiotherapy is still uncertain because of the controversial outcomes.

    Authors: Carmen Giannantonio, Patrizia Papacci, Roberta Ciarniello, Mikael Ghennet Tesfagabir, Velia Purcaro, Francesco Cota, Carla Maria Semeraro and Costantino Romagnoli

    Citation: Italian Journal of Pediatrics 2010 36:65

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  29. Content type: Research

    Persistent pulmonary hypertension of the newborn (PPHN) is a severe condition that determines a profound brain hypoxia. Inhaled nitric oxide was approved for the treatment of PPHN since the end of the 1990s. T...

    Authors: Anna Berti, Augusta Janes, Riccardo Furlan and Francesco Macagno

    Citation: Italian Journal of Pediatrics 2010 36:45

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  30. Content type: Case report

    Liver failure in neonates is a rare but often fatal disease. Trisomy 21 is not usually associated with significant infantile liver disease. If present, hepatic dysfunction in an infant with Trisomy 21 is likel...

    Authors: Erin Neil, Josef Cortez, Aparna Joshi, Erawati V Bawle, Janet Poulik, Mark Zilberman, Mohammad F El-Baba and Beena G Sood

    Citation: Italian Journal of Pediatrics 2010 36:38

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  31. Content type: Debate

    Two premature twins (33 weeks gestation) were born to a woman who had used paroxetine during pregnancy for an anxiety-depression disorder. They were admitted to the NICU, where they showed prolonged RDS, cardi...

    Authors: Maria Marsella, Elisabetta Ubaldini, Agostina Solinas and Pietro Guerrini

    Citation: Italian Journal of Pediatrics 2010 36:27

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  32. Content type: Case report

    Classical Poland Syndrome (PS) is characterized by unilateral, partial or complete absence of the sternocostal head of the major pectoral muscle and brachysyndactyly of fingers on the same side.

    Authors: Doriana Lacorte, Maria Marsella and Pietro Guerrini

    Citation: Italian Journal of Pediatrics 2010 36:21

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  33. Content type: Research

    The perfusion index, derived from the pulse oximeter signal, seems to be an accurate predictor for high illness severity in newborns. The aim of this study was to determine the perfusion index values of clinic...

    Authors: Francesco Cresi, Emanuela Pelle, Roberto Calabrese, Luciana Costa, Daniela Farinasso and Leandra Silvestro

    Citation: Italian Journal of Pediatrics 2010 36:6

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  34. Content type: Case report

    Pyloric atresia (PA) is a very rare condition. Its incidence is approximately 1 in 100,000 newborns and constitutes about 1% of all intestinal atresias. We describe the neonatal course of a peculiar case of ty...

    Authors: Enrico Zecca, Mirta Corsello, Claudio Pintus, Lorenzo Nanni and Susanna Zecca

    Citation: Italian Journal of Pediatrics 2010 36:3

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  35. Content type: Case report

    Congenital afibrinogenemia is a very rare inherited coagulation disorder, characterized by virtual absence of plasma fibrinogen (factor I). There are only about 250 cases reported in the world literature [1]. We ...

    Authors: Gopakumar Hariharan, Sivji Ramachandran and Rajiv Parapurath

    Citation: Italian Journal of Pediatrics 2010 36:1

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