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Neonatology – Italian Society of Neonatology (SIN)

This section covers all aspects of neonatal and fetal health, disease, treatment, and outcomes.

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  1. Congenital nephrotic syndrome (CNS), which is defined as heavy proteinuria, hypoalbuminemia, hyperlipidemia and edema, is most caused by monogenic defects in structural proteins of the glomerular filtration ba...

    Authors: Liangliang Li, Zhi Yi, Hongmin Xi, Lili Ma, Hui Shao, Wenwen Wang, Hong Pan, Miaomiao Li and Hong Jiang
    Citation: Italian Journal of Pediatrics 2019 45:109
    Content type: Case report Published on:

  2. The treatment of patent ductus arteriosus (PDA) in very low birth weight (VLBW) infants remains a challenge. The ability to predict which infants will respond to indomethacin could spare some from the risks of...

    Authors: Janardhan Mydam, Alok Rastogi and Zahra J. Naheed
    Citation: Italian Journal of Pediatrics 2019 45:107
    Content type: Research Published on:

  3. Deleterious consequences of the management of respiratory distress syndrome (RDS) with invasive ventilation have led to more in-depth investigation of non-invasive ventilation (NIV) modalities. NIV has signifi...

    Authors: Dhivya Lakshmi Permall, Asfia Banu Pasha and Xiao-qing Chen
    Citation: Italian Journal of Pediatrics 2019 45:105
    Content type: Review Published on:

  4. This article describes the detailed project aimed to realize a dedicated ground ambulance for neonatal emergency transport service (NETS). To date, the European Community rules specify requirements for the des...

    Authors: Carlo Bellini, Martina de Biasi, Maurizio Gente, Luca A. Ramenghi, Roberto Aufieri, Diego Minghetti, Silvia Pericu, Martina Cavalieri and Niccolò Casiddu
    Citation: Italian Journal of Pediatrics 2019 45:97
    Content type: Research Published on:

  5. Sudden unexpected postnatal collapse of presumably healthy neonates during early skin-to-skin contact is a rare, yet recognized occurrence, associated with a high risk of mortality and morbidity. A survey was ...

    Authors: Michelangelo Barbaglia, Enrico Finale, Silvia Noce, Alessandro Vigo, Cesare Arioni, Raffaella Visentin, Elisabetta Scurati-Manzoni and Andrea Guala
    Citation: Italian Journal of Pediatrics 2019 45:95
    Content type: Research Published on:

  6. Enteroviruses (EVs) are an important cause of illness, especially in neonates and young infants. Clinical and laboratory findings at different ages, brain imaging, and outcomes have been inadequately investiga...

    Authors: Alberto Berardi, Marcello Sandoni, Carlotta Toffoli, Alessandra Boncompagni, William Gennari, Maria Barbara Bergamini, Laura Lucaccioni and Lorenzo Iughetti
    Citation: Italian Journal of Pediatrics 2019 45:94
    Content type: Research Published on:

  7. The purpose of this study was to analyze the growth status and to identify the risk factors that influence the catch-up growth of preterm infants after discharge and to provide evidence for feeding strategies ...

    Authors: Xiaomei Liu, Biru Luo, Wentao Peng, Fei Xiong, Fan Yang and Jinhui Wu
    Citation: Italian Journal of Pediatrics 2019 45:87
    Content type: Research Published on:

  8. Turner syndrome (45,X), accounts for 1–2% of conceptions which typically miscarry early in the first trimester. Cases detected prenatally often present with cystic hygroma, which is an ultrasound marker for an...

    Authors: Hai-Ying Chen, Jian-Qiong Zheng and Hong-Ping Zhang
    Citation: Italian Journal of Pediatrics 2019 45:85
    Content type: Case report Published on:

  9. Fibreoptic Phototherapy (FPT) allows to lower total serum bilirubin (TSB) levels in healthy neonates maintained in rooming-in with their mothers. The 2004 Cochrane review showed that, differently from preterm ...

    Authors: R. Luciano, G. Mancini, F. Cota, A. Romano, V. Purcaro, F. Lerro, M. Corsello and G. Vento
    Citation: Italian Journal of Pediatrics 2019 45:68
    Content type: Research Published on:

  10. Neonatal adrenal hemorrhage is a relatively uncommon condition (0.2–0.55%). Various risk factors have been reported in addition to birth asphyxia, such as sepsis, coagulation disorders, traumatic delivery, and...

    Authors: M. S. Toti, P. Ghirri, A. Bartoli, C. Caputo, E. Laudani, F. Masoni, L. Mele and R. Bernardini
    Citation: Italian Journal of Pediatrics 2019 45:58
    Content type: Case report Published on:

  11. Preterm birth and feeding are the most important pathogenic factors of neonatal necrotizing enterocolitis (NEC). Metabonomic has been widely used in the diagnosis and treatment of other diseases, but there is ...

    Authors: Fusheng Wang, Weizhong Li, Guanghuan Wang, Menglu Yu, Jun Zhong, Chenbin Xu, Danli Li and Yongcui Zhou
    Citation: Italian Journal of Pediatrics 2019 45:54
    Content type: Research Published on:

  12. Despite regionalization of perinatal care provides for the “in utero” transfer of high-risk pregnancies, there will always be a number of neonates who undergo acute inter-facility transport. The presence of a ...

    Authors: Maurizio Gente, Roberto Aufieri, Rocco Agostino, Tiziana Fedeli, Maria Grazia Calevo, Paolo Massirio and Carlo Bellini
    Citation: Italian Journal of Pediatrics 2019 45:51
    Content type: Research Published on:

  13. Congenital anomalies of the kidney and urinary tract (CAKUTs) are some of the most common birth defects affecting newborns. CAKUTs often have poor birth outcomes owing to the limited experience of physicians i...

    Authors: Zhong-yi Li, Yan-min Chen, Li-qian Qiu, Dan-qing Chen, Chong-gao Hu, Jian-yun Xu and Xiao-hui Zhang
    Citation: Italian Journal of Pediatrics 2019 45:50
    Content type: Research Published on:

  14. Low birth weight is defined as infant born with weight of less than 2500 g. It is one of the major public health problems worldwide. In Ethiopia, there are limited evidences on factors contributing to low birt...

    Authors: Melese Siyoum and Teshome Melese
    Citation: Italian Journal of Pediatrics 2019 45:48
    Content type: Research Published on:

  15. Preterm birth is a health and social problem, considered the leading cause of neonatal mortality worldwide. It is associated with higher rates of neurodevelopmental morbidity, sensorineural impairments and oth...

    Authors: Roberta Granese, Eloisa Gitto, Gabriella D’Angelo, Raffaele Falsaperla, Giovanni Corsello, Donatella Amadore, Gloria Calagna, Ilaria Fazzolari, Roberta Grasso and Onofrio Triolo
    Citation: Italian Journal of Pediatrics 2019 45:45
    Content type: Research Published on:

  16. We aimed to survey Delivery Room and Neonatal Intensive Care Unit (NICU) respiratory strategies dedicated to the extremely low gestational age newborn (ELGAN – GA < 28 wks) in Italy.

    Authors: Flavia Petrillo, Camilla Gizzi, Gianfranco Maffei, Piero G. Matassa, Maria Luisa Ventura, Cinzia Ricci, Roberta Pastorino and Giovanni Vento
    Citation: Italian Journal of Pediatrics 2019 45:44
    Content type: Research Published on:

  17. The term “Lotus Birth” identifies the practice of not cutting the umbilical cord and of leaving the placenta attached to the newborn after its expulsion until it detaches spontaneously, which generally occurs ...

    Authors: Alessandro Bonsignore, Francesca Buffelli, Rosagemma Ciliberti, Francesco Ventura, Andrea Molinelli and Ezio Fulcheri
    Citation: Italian Journal of Pediatrics 2019 45:39
    Content type: Debate Published on:

  18. In order to give a new contribution to the knowledge of the psycho-physical, behavioral and socio-relational development of the individuals who were born at neurological risk, we have carried out a research wo...

    Authors: Enrico Gasparrini, Francesca Rosati and Maria Teresa Gaetti
    Citation: Italian Journal of Pediatrics 2019 45:38
    Content type: Research Published on:

  20. The association between macrolides use and subsequent occurrence of infantile hypertrophic pyloric stenosis (IHPS) is still debatable. The aim of this study was to conduct a systematic review and meta-analysis...

    Authors: Hamdi H. Almaramhy and Abdulmohsen H. Al-Zalabani
    Citation: Italian Journal of Pediatrics 2019 45:20
    Content type: Review Published on:

  21. Although Pre-lacteal feeding is a barrier for implementation of optimal breastfeeding practices and increases the risk of neonatal illness and mortality, still it is continued as a deep-rooted nutritional malp...

    Authors: Esayas Aydiko Amele, Birhanu wondimeneh Demissie, Kalkidan Wondwossen Desta and Emebet Berhane Woldemariam
    Citation: Italian Journal of Pediatrics 2019 45:15
    Content type: Research Published on:

  22. Globally, more than 20 million infants are born with low birth weight. The risk of neonatal mortality among low birth weight infants is 25 to 30 times greater than neonates with birth weight ≥ 2500 g. Low birth w...

    Authors: Daniale Tekelia Ekubagewargies, Destaye Guadie Kassie and Wubet Worku Takele
    Citation: Italian Journal of Pediatrics 2019 45:7
    Content type: Research Published on:

  23. Prematurity accounts about 1 million neonatal deaths worldwide and the second causes of both neonatal and under five-child mortality. Neonatal mortality accounts for 43% of under-five child mortality in Ethiop...

    Authors: Ayenew Engida Yismaw, Abebaw Addis Gelagay and Malede Mequanent Sisay
    Citation: Italian Journal of Pediatrics 2019 45:4
    Content type: Research Published on:

  24. A physiologic test for estimating BPD rate has been developed by Walsh and collaborators. Actually there are not standard criteria for weaning from CPAP and/or oxygen therapy the premature babies. Aim of this ...

    Authors: Giovanni Vento, Valentina Vendettuoli, Claudia Aurilia, Milena Tana, Chiara Tirone, Alessandra Lio, Piero Giuseppe Matassa, Francesca Priolo, Piero Catenazzi, Mirta Corsello, Enrico Zecca and Fabio Mosca
    Citation: Italian Journal of Pediatrics 2019 45:2
    Content type: Research Published on:

  25. Optimum early postnatal growth is critical for early and later health of preterm infants. Postnatal length and weight growth velocities and their associated perinatal factors in healthy late preterm infants wi...

    Authors: Li Zhang, Yan Li, Shuang Liang, Xiao-Juan Liu, Feng-Ling Kang and Gui-Mei Li
    Citation: Italian Journal of Pediatrics 2019 45:1
    Content type: Research Published on:

  26. During the last epidemic season of bronchiolitis (S2, years 2016–2017) we performed a single Centre analysis in inborn infant of 30+ 0–32+ 6 gestational age and age < 12 months who did not receive prophylaxis wit...

    Authors: Simonetta Picone, Adele Fabiano, Davide Roma, Federico Di Palma and Piermichele Paolillo
    Citation: Italian Journal of Pediatrics 2018 44:148
    Content type: Letter to the Editor Published on:

  27. Different primary studies in Ethiopia showed the burden of low birth weight. However, variation among those studies was seen. This study was aimed to estimate the national prevalence and associated factors of ...

    Authors: Aklilu Endalamaw, Eshetu Haileselassie Engeda, Daniale Tekelia Ekubagewargies, Getaneh Mulualem Belay and Mekuriaw Alemayehu Tefera
    Citation: Italian Journal of Pediatrics 2018 44:141
    Content type: Review Published on:

  28. Among breastfeeding determinants, the marketing of breast milk substitutes might contribute to suboptimal breastfeeding rates. The aim of this study was to investigate the effect of receiving information on br...

    Authors: Fabio Mosca, Paola Roggero, Francesca Garbarino, Daniela Morniroli, Beatrice Bracco, Laura Morlacchi, Domenica Mallardi, Maria Lorella Gianni and Dario Consonni
    Citation: Italian Journal of Pediatrics 2018 44:134
    Content type: Research Published on:

  29. Neonatal seizures are the most common neurological event in newborns, showing higher prevalence in preterm than in full-term infants. In the majority of cases they represent acute symptomatic phenomena, the ma...

    Authors: Carlotta Spagnoli, Raffaele Falsaperla, Michela Deolmi, Giovanni Corsello and Francesco Pisani
    Citation: Italian Journal of Pediatrics 2018 44:115
    Content type: Review Published on:

  30. Fetal supraventricular tachycardia (SVT), characterized by fetal heart rate between 220 and 260 bpm, is a rare but most commonly encountered fetal cardiac arrhythmia in pregnancy that may be associated with ad...

    Authors: Vincenzo Zanardo, Alphonse Simbi, Matteo Parotto, Lorenzo Severino, Riccardo Carta, Pietro Guerrini and Gianluca Straface
    Citation: Italian Journal of Pediatrics 2018 44:111
    Content type: Case report Published on:

    The Correction to this article has been published in Italian Journal of Pediatrics 2019 45:21

  31. The neonatal period is only 1/60th of the first 5 years of life but it accounts for 63% of all infant deaths and 44% of all under-five deaths in Ethiopia. Most causes of neonatal death are preventable with clean ...

    Authors: Tadese Ejigu Tafere, Mesganaw Fanthahun Afework and Alemayehu Worku Yalew
    Citation: Italian Journal of Pediatrics 2018 44:105
    Content type: Research Published on:

  32. Parenteral nutrition-associated cholestasis (PNAC) is a serious complication in preterm infants receiving prolonged parenteral nutrition. Soybean lipid emulsion (SLE) seems to have a role in its pathogenesis, ...

    Authors: Simonetta Costa, Rossella Iannotta, Luca Maggio, Giovanni Barone, Francesca Serrao and Giovanni Vento
    Citation: Italian Journal of Pediatrics 2018 44:101
    Content type: Research Published on:

  33. Continuous glucose monitoring using subcutaneous sensors is useful in the management of glucose control in neonatal intensive care. We evaluated feasibility and reliability of a continuous glucose monitoring s...

    Authors: Alessandro Perri, Lucia Giordano, Mirta Corsello, Francesca Priolo, Giovanni Vento, Enrico Zecca and Eloisa Tiberi
    Citation: Italian Journal of Pediatrics 2018 44:99
    Content type: Research Published on:

  34. Congenital space-occupying thoracic malformations and diaphragmatic hernia have in common pulmonary hypoplasia. Our study aims to assess cardiac involvement during post-natal adaptation.

    Authors: Ingrid Anne Mandy Schierz, Mario Giuffrè, Ettore Piro, Maria Clara Leone, Giuseppa Pinello and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2018 44:98
    Content type: Research Published on:

  35. Human milk (HM) is the best feeding for premature infants. When own mother’s milk (OMM) is insufficient or unavailable, pasteurized donor human milk (PDHM) and preterm formula (PF) are the alternative nutritio...

    Authors: Simonetta Costa, Luca Maggio, Giovanni Alighieri, Giovanni Barone, Francesco Cota and Giovanni Vento
    Citation: Italian Journal of Pediatrics 2018 44:96
    Content type: Research Published on:

  37. Neonatal priapism is a rare condition with only 26 described cases in literature since 1879. It is defined as a persistent penile erection occurring in the first 28 days of life, lasting at least 4 h that usua...

    Authors: Claudia Fanni, Maria Antonietta Marcialis, Maria Cristina Pintus, Cristina Loddo and Vassilios Fanos
    Citation: Italian Journal of Pediatrics 2018 44:85
    Content type: Review Published on:

  38. Necrotizing enterocolitis continues to be a devastating disease process for very low birth weight infants in Neonatal Intensive Care Units. The aetiology and pathogenesis of necrotizing enterocolitis are not d...

    Authors: Gabriella D’Angelo, Pietro Impellizzeri, Lucia Marseglia, Angela Simona Montalto, Tiziana Russo, Ignazio Salamone, Raffaele Falsaperla, Giovanni Corsello, Carmelo Romeo and Eloisa Gitto
    Citation: Italian Journal of Pediatrics 2018 44:84
    Content type: Review Published on:

  40. Newborns with congenital diaphragmatic hernia (CDH) and esophageal atresia (EA) might experience breastfeeding difficulties. The aim of this study was to detect the prevalence of breastfeeding in newborns with...

    Authors: G Salvatori, S Foligno, M Massoud, F Piersigilli, P Bagolan and A Dotta
    Citation: Italian Journal of Pediatrics 2018 44:75
    Content type: Research Published on:

  41. Strategies to prevent early-onset sepsis (EOS) have led to a substantial decline in many countries. However, one of the most controversial topics in neonatology is the management of asymptomatic full-term and ...

    Authors: Alberto Berardi, Chryssoula Tzialla, Laura Travan, Jenny Bua, Daniele Santori, Milena Azzalli, Caterina Spada and Laura Lucaccioni
    Citation: Italian Journal of Pediatrics 2018 44:73
    Content type: Commentary Published on:

  42. Most Neonatal Intensive Care Units (NICUs) in China have restricted visiting policies for parents. This also implicates that parents are not involved in the care of their infant. Family Integrated Care (FIC), ...

    Authors: Shi-wen He, Yue-e Xiong, Li-hui Zhu, Bo Lv, Xi-rong Gao, Hua Xiong, Huan Wang, Hua-rong Shi and Jos M. Latour
    Citation: Italian Journal of Pediatrics 2018 44:65
    Content type: Research Published on:

  43. Ethiopia is among the countries with the highest neonatal mortality with the rate of 37 deaths per 1000 live births. In spite of many efforts by the government and other partners, non significant decline has b...

    Authors: Tilahun Tewabe, Yenatfanta Mehariw, Eyerusalem Negatie and Bertukan Yibeltal
    Citation: Italian Journal of Pediatrics 2018 44:57
    Content type: Research Published on:

  44. Birth asphyxia is defined as the presence of hypoxia, hypercapnia, and acidosis leading the newborn to systemic disturbances probably electrolyte disturbance also. Knowledge of these electrolyte disturbances i...

    Authors: Jitendra Thakur, Nisha Keshary Bhatta, Rupa Rajbhandari Singh, Prakash Poudel, Madhab Lamsal and Anjum Shakya
    Citation: Italian Journal of Pediatrics 2018 44:56
    Content type: Research Published on:

  45. Inhaled nitric oxide (iNO) has been approved for the treatment of persistent pulmonary hypertension of the newborn (PPHN) in term and near-term newborns. Its role in the management of persistent pulmonary hype...

    Authors: Martina Busè, Francesco Graziano, Fabio Lunetta, Giorgio Sulliotti and Vincenzo Duca
    Citation: Italian Journal of Pediatrics 2018 44:55
    Content type: Case report Published on:

  46. Vitamin K, a fat soluble vitamin, is a necessary cofactor for the activation of coagulation factors II, VII, IX, X, and protein C and S. In neonatal period, vitamin K deficiency may lead to Vitamin K Deficienc...

    Authors: Maria Rosaria Marchili, Elisa Santoro, Alessandra Marchesi, Simona Bianchi, Lelia Rotondi Aufiero and Alberto Villani
    Citation: Italian Journal of Pediatrics 2018 44:36
    Content type: Case report Published on:

  48. Unilateral absence of the pulmonary artery (UAPA) is a rare congenital malformation often associated with other cardiac anomalies; however it may occur as an isolated lesion. Isolated absence of the right pulm...

    Authors: Akamin Raymond, Ettore Pedretti, Giuseppina Privitera, Cristina Cicero and Giacomo Biasucci
    Citation: Italian Journal of Pediatrics 2018 44:27
    Content type: Case report Published on:

  49. The aim of this study was to define different characteristics of infants with esophageal atresia and correlations with neonatal level of care, morbidity and mortality occurring during hospital stay.

    Authors: Ettore Piro, Ingrid Anne Mandy Schierz, Mario Giuffrè, Giovanni Cuffaro, Simona La Placa, Vincenzo Antona, Federico Matina, Giuseppe Puccio, Marcello Cimador and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2018 44:19
    Content type: Research Published on:

  50. To determine longitudinally the relationship between serum 25-hydroxyvitamin D (vitamin D) and vitamin D-binding protein (DBP) levels in mother-neonate pairs and evaluate the efficiency of prophylactic vitamin...

    Authors: Hakan Doneray, Remziye Seda Yesilcibik, Esra Laloglu, Metin Ingec and Zerrin Orbak
    Citation: Italian Journal of Pediatrics 2018 44:15
    Content type: Research Published on:

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