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Neonatology and Fetal Medicine

This section covers all aspects of neonatal and fetal health, disease, treatment, and outcomes.

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  2. We assessed the incidence of infants born small-for-gestational-age (SGA) and large-for-gestational-age (LGA) in an Italian cohort over 20 years (1993–2013). Furthermore, we investigated maternal factors assoc...

    Authors: Valentina Chiavaroli, Valeria Castorani, Paola Guidone, José G. B. Derraik, Marco Liberati, Francesco Chiarelli and Angelika Mohn

    Citation: Italian Journal of Pediatrics 2016 42:42

    Content type: Research

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  3. The most widespread method for the treatment of donor milk is the Holder pasteurization (HoP). The available literature data show that HoP may cause degradation of some bioactive components. The aim of this st...

    Authors: Chiara Peila, Alessandra Coscia, Enrico Bertino, Maria Cavaletto, Stefano Spertino, Sara Icardi, Claudia Tortone, Gerard H. A. Visser and Diego Gazzolo

    Citation: Italian Journal of Pediatrics 2016 42:36

    Content type: Research

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  4. Neonatal units’ volume of activity, and other quantitative and qualitative variables, such as staffing, workload, work environment, care organization and geographical location, may influence the outcome of hig...

    Authors: Carlo Corchia, Simone Fanelli, Luigi Gagliardi, Roberto Bellù, Antonello Zangrandi, Anna Persico and Rinaldo Zanini

    Citation: Italian Journal of Pediatrics 2016 42:34

    Content type: Research

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  5. Continuous glucose monitoring using subcutaneous sensors has been validated in adults and children with diabetes, and was found to be useful in the management of glucose control. We aimed to assess feasibility...

    Authors: Eloisa Tiberi, Francesco Cota, Giovanni Barone, Alessandro Perri, Valerio Romano, Rossella Iannotta, Costantino Romagnoli and Enrico Zecca

    Citation: Italian Journal of Pediatrics 2016 42:29

    Content type: Research

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  7. Congenital hearing loss is the most frequent birth defect. The American Academy of Pediatrics and the Joint Committee on Infant Hearing established quality of care process indicators for Universal Newborn Hear...

    Authors: Carlo Giacomo Leo, Pierpaolo Mincarone, Saverio Sabina, Giuseppe Latini and John B. Wong

    Citation: Italian Journal of Pediatrics 2016 42:15

    Content type: Debate

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  8. To explore the association between maternal alcohol consumption and/or binge drinking and congenital heart defects (CHDs), we conducted a meta-analysis for more sufficient evidence on this issue.

    Authors: Zhongyuan Wen, Di Yu, Weiyan Zhang, Changfeng Fan, Liang Hu, Yu Feng, Lei Yang, Zeyu Wu, Runsen Chen, Ke-jie Yin and Xuming Mo

    Citation: Italian Journal of Pediatrics 2016 42:12

    Content type: Review

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  9. In addition to surfactant deficiency, increase of lung fluid content and secretion of fluid derived from the blood participate in the pathogenesis of RDS in newborns.

    Authors: Masoud Dehdashtian, Arash Malakian, Mohammad Reza Aramesh, Ali Mazori, Mohammad Hasan Aletayeb, Afsaneh Shirani and Shiva Bashirnejad

    Citation: Italian Journal of Pediatrics 2016 42:6

    Content type: Research

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  10. Neonatal Lupus Erythematosus (NLE) is an uncommon autoimmune disease characterized by cutaneous, hepatic, hematological, neurological and cardiac involvement.

    Authors: Francesco Savino, Serena Viola, Valentina Tarasco, Emanuela Locatelli, Alberto Ricagni and Paola Coppo

    Citation: Italian Journal of Pediatrics 2016 42:1

    Content type: Case report

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  11. Respiratory Syncytial Virus infections are one of the leading causes of severe respiratory diseases that require hospitalization and, in some cases, intensive care. Once resolved, there may be respiratory sequ...

    Authors: Lina Bollani, Eugenio Baraldi, Gaetano Chirico, Andrea Dotta, Marcello Lanari, Antonello Del Vecchio, Paolo Manzoni, Antonio Boldrini, Piermichele Paolillo, Sandra Di Fabio, Luigi Orfeo, Mauro Stronati and Costantino Romagnoli

    Citation: Italian Journal of Pediatrics 2015 41:97

    Content type: Review

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  12. Infant massage is a natural way for caregivers to improve health, sleep patterns, and reduce colic. We aimed to investigate the effects of infant massage on neonates with jaundice who are also receiving photot...

    Authors: Chien-Heng Lin, Hsiu-Chuan Yang, Chien-Sheng Cheng and Chin-En Yen

    Citation: Italian Journal of Pediatrics 2015 41:94

    Content type: Research

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  13. Necrotizing enterocolitis (NEC) affects predominantly preterm infants, who have specific risk factors leading to intestinal dysbiosis. Manipulations of gut microbiota through probiotics have the potential to prev...

    Authors: Arianna Aceti, Davide Gori, Giovanni Barone, Maria Luisa Callegari, Antonio Di Mauro, Maria Pia Fantini, Flavia Indrio, Luca Maggio, Fabio Meneghin, Lorenzo Morelli, Gianvincenzo Zuccotti and Luigi Corvaglia

    Citation: Italian Journal of Pediatrics 2015 41:89

    Content type: Review

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  14. Thymic enlargement is a common and physiological finding in children and neonates’ X-rays, but it is usually asymptomatic. Occasionally it can cause respiratory distress. In most cases the aetiology of this e...

    Authors: Giancarlo Gargano, Anna Lucia Paltrinieri, Claudio Gallo, Luciana Di Pancrazio, Maria Federica Roversi and Fabrizio Ferrari

    Citation: Italian Journal of Pediatrics 2015 41:88

    Content type: Case report

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  15. Fraser Syndrome is a rare, autosomal recessive syndrome. It’s characterized primarily by cryptophthalmos, syndactyly and urogenital malformation. Respiratory malformations are frequently present and not taken ...

    Authors: Giuseppe De Bernardo, Maurizio Giordano, Antonino Di Toro, Desiree Sordino and Daniele De Brasi

    Citation: Italian Journal of Pediatrics 2015 41:86

    Content type: Case Report

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  16. Neonates born with meconium stained amniotic fluid (MSAF) can develop feed intolerance during first few days of post -natal period. A randomized controlled trial was conducted with the objectives of to find ou...

    Authors: Lokraj Shah, Gauri Shankar Shah, Rupa Rajbhandari Singh, Hanoon Pokharel and Om Prakash Mishra

    Citation: Italian Journal of Pediatrics 2015 41:85

    Content type: Research

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  17. Down syndrome (DS) is one of the most common chromosomal abnormalities among newborns. In recent years advances in perinatal and neonatal care have improved chance of survival for the children with DS. The obj...

    Authors: Tatjana Glivetic, Urelija Rodin, Milan Milosevic, Diana Mayer, Boris Filipovic-Grcic and Maida Seferovic Saric

    Citation: Italian Journal of Pediatrics 2015 41:81

    Content type: Research

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  19. Therapeutic hypothermia (TH) has become standard care in newborns with moderate to severe hypoxic ischemic encephalopathy (HIE), and the 2 most commonly used methods are selective head cooling (SHC) and whole ...

    Authors: Yalçın Çelik, Aytuğ Atıcı, Selvi Gülaşı, Khatuna Makharoblıdze, Gülçin Eskandari, Mehmet Ali Sungur and Serin Akbayır

    Citation: Italian Journal of Pediatrics 2015 41:79

    Content type: Research

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  22. Aim of this study was to estimate the cost that is borne by the Italian National Health Service, families, and social security due to very low birth weight infants (VLBWIs) without prematurity-related morbidit...

    Authors: Maria Caterina Cavallo, Attilio Gugiatti, Giovanni Fattore, Simone Gerzeli, Dario Barbieri and Rinaldo Zanini

    Citation: Italian Journal of Pediatrics 2015 41:59

    Content type: Research

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  24. The objective of our study is to evaluate the correlation between epidural analgesia during labor, start of breastfeeding and type of maternal-neonatal care.

    Authors: Antonio Alberto Zuppa, Giovanni Alighieri, Riccardo Riccardi, Maria Cavani, Alma Iafisco, Francesco Cota and Costantino Romagnoli

    Citation: Italian Journal of Pediatrics 2014 40:82

    Content type: Research

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  25. Aplasia cutis congenita (ACC) is usually located on the hairy scalp, on the vertex of the head, but can also occur in other locations, such as limbs, trunk. Congenital skin aplasia on the lower limb is very ra...

    Authors: Agata Pająk, Anna Szczygieł, Dorota Paluszyńska and Barbara Królak-Olejnik

    Citation: Italian Journal of Pediatrics 2014 40:88

    Content type: Case report

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  27. Kangaroo mother care (KMC) has been widely used to improve the care of preterms and low birth weight infants. However, very little is known about cerebral hemodynamics responses in preterm infants during KMC i...

    Authors: Afaf A Korraa, Alyaa A I El Nagger, Ragaa Abd El-Salam Mohamed and Noha M Helmy

    Citation: Italian Journal of Pediatrics 2014 40:83

    Content type: Research

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  28. The World Health Organisation has recommended the use of anthropometric measurements as birth weight surrogates. However, it has been found that cut-off points for these anthropometric measurements vary across...

    Authors: Ikenna K Ndu, Stella N Ibeziako, Egbuna O Obidike, Gilbert N Adimora, Benedict O Edelu, Josephat M Chinawa, Isaac N Asinobi and Nwachinemere D Uleanya

    Citation: Italian Journal of Pediatrics 2014 40:81

    Content type: Research

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  30. Early discharge of mother/neonate dyad has become a common practice, and its effects are measured by readmission rates. We evaluated the safety of early discharge followed by an individualized Follow-up progra...

    Authors: Maria Pia De Carolis, Carmen Cocca, Elisabetta Valente, Serafina Lacerenza, Serena Antonia Rubortone, Antonio Alberto Zuppa and Costantino Romagnoli

    Citation: Italian Journal of Pediatrics 2014 40:70

    Content type: Research

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  31. Current literature provides limited data on the hemodynamic changes that may occur during bi-level continuous positive airway pressure (CPAP) support in preterm infants. However, the application of a positive ...

    Authors: Giulia Aquilano, Silvia Galletti, Arianna Aceti, Francesca Vitali and Giacomo Faldella

    Citation: Italian Journal of Pediatrics 2014 40:60

    Content type: Research

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  32. To evaluate short-term respiratory outcomes in late preterm infants (LPI) compared with those of term infants (TI).

    Authors: Miria Natile, Maria Luisa Ventura, Marco Colombo, Davide Bernasconi, Anna Locatelli, Cristina Plevani, Maria Grazia Valsecchi and Paolo Tagliabue

    Citation: Italian Journal of Pediatrics 2014 40:52

    Content type: Research

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  33. Twins, compared to singletons, have an increased risk of perinatal mortality and morbidity, due mainly to a higher prevalence of preterm birth and low birthweight. Intrauterine growth restriction (IUGR) is als...

    Authors: Giuseppe Puccio, Mario Giuffré, Maria Piccione, Ettore Piro, Valentina Malerba and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2014 40:43

    Content type: Research

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  34. Ability to maintain a normal body temperature in an open crib is an important physiologic competency generally requested to discharge preterm infants from the hospital. The aim of this study is to assess the f...

    Authors: Giovanni Barone, Mirta Corsello, Patrizia Papacci, Francesca Priolo, Costantino Romagnoli and Enrico Zecca

    Citation: Italian Journal of Pediatrics 2014 40:41

    Content type: Research

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  35. The best criteria for surfactant treatment in the perinatal period are unknown and this makes it of interest to consider the possible economic implications of lessening the use of more restrictive criteria.

    Authors: Carlo Dani, Roberto Ravasio, Leonardo Fioravanti and Maria Circelli

    Citation: Italian Journal of Pediatrics 2014 40:40

    Content type: Research

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  37. Surfactant treatment reduces respiratory morbidity and mortality in preterm infants. Data on its haemodynamic consequences are conflicting. The aim was to characterise the haemodynamic effects of surfactant tr...

    Authors: Francesca Vitali, Silvia Galletti, Arianna Aceti, Giulia Aquilano, Marianna Fabi, Anna Balducci and Giacomo Faldella

    Citation: Italian Journal of Pediatrics 2014 40:26

    Content type: Research

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  38. Aim of our study is to analyze the immunological status in pregnancy for two main TORCH agents, Toxoplasma and Cytomegalovirus (CMV), and the results of group B streptococcus (GBS) screening, assessing the ris...

    Authors: Giuseppe Puccio, Cinzia Cajozzo, Laura Antonella Canduscio, Lucia Cino, Amelia Romano, Maria Gabriella Schimmenti, Mario Giuffrè and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2014 40:23

    Content type: Research

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  39. Inhibitors of the cyclo-oxygenase component of prostaglandin-H2 synthetase, namely indomethacin and ibuprofen, are commonly used in the treatment of hemodynamically significant patent ductus arteriosus. These dru...

    Authors: Gianluca Terrin, Francesca Conte, Antonella Scipione, Erica Bacchio, Maria Giulia Conti, Rosalia Ferro, Flavia Ventriglia and Mario De Curtis

    Citation: Italian Journal of Pediatrics 2014 40:21

    Content type: Case report

    Published on:

  40. Hyperbilirubinaemia is one of the most frequent problems in otherwise healthy newborn infants. Early discharge of the healthy newborn infants, particularly those in whom breastfeeding is not fully established,...

    Authors: Costantino Romagnoli, Giovanni Barone, Simone Pratesi, Francesco Raimondi, Letizia Capasso, Enrico Zecca and Carlo Dani

    Citation: Italian Journal of Pediatrics 2014 40:11

    Content type: Research

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  41. About 90,000 preterm infants or babies with birth defects are born in Italy every year, nearly 250 per day. These congenital conditions and their outcomes represent the most important burden of disease affecti...

    Authors: Carlo Corchia and Pierpaolo Mastroiacovo

    Citation: Italian Journal of Pediatrics 2013 39:68

    Content type: Commentary

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  42. To investigate the effectiveness of IgM-enriched immunoglobulins (IgM-eIVIG) in reducing short-term mortality of neonates with proven late-onset sepsis.

    Authors: Letizia Capasso, Angela Carla Borrelli, Claudia Parrella, Silvia Lama, Teresa Ferrara, Clara Coppola, Maria Rosaria Catania, Vita Dora Iula and Francesco Raimondi

    Citation: Italian Journal of Pediatrics 2013 39:63

    Content type: Research

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  43. To evaluate the association between the genetic polymorphism of the solute carrier organic anion transporter family member 1B1 (SLCO1B1, also known as organic anion transport polypeptide C) and hyperbilirubine...

    Authors: Jiebo Liu, Jun Long, Shaofang Zhang, Xiaoyan Fang and Yuyuan Luo

    Citation: Italian Journal of Pediatrics 2013 39:49

    Content type: Research

    Published on:

  44. Transcutaneous bilirubinometry is widely used to predict hyperbilirubinemia by using several devices. The aim of this study was to compare the predictive ability of BiliCheck vs JM-103 in identifying neonates ...

    Authors: Costantino Romagnoli, Piero Catenazzi, Giovanni Barone, Lucia Giordano, Riccardo Riccardi, Antonio Alberto Zuppa and Enrico Zecca

    Citation: Italian Journal of Pediatrics 2013 39:46

    Content type: Research

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  45. VATER association was first described in 1972 by Quan and Smith as an acronym which identifies a non-random co-occurrence of Vertebral anomalies, Anal atresia, Tracheoesophageal fistula and/or Esophageal atres...

    Authors: Simona La Placa, Mario Giuffrè, Antonella Gangemi, Stefania Di Noto, Federico Matina, Federica Nociforo, Vincenzo Antona, Maria Rita Di Pace, Maria Piccione and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2013 39:45

    Content type: Research

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  46. This study aims to investigate the incidence and the relative risk factors of retinopathy of prematurity (ROP) and posterior-ROP (P-ROP): ROP in Zone I and posterior Zone II, as well as to analyze the occurren...

    Authors: Cesarina Borroni, Carla Carlevaro, Sabrina Morzenti, Elena De Ponti, Valentina Bozzetti, Vito Console, Salvatore Capobianco and Paolo E Tagliabue

    Citation: Italian Journal of Pediatrics 2013 39:43

    Content type: Research

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  47. Methadone is commonly prescribed as a substitute for illicit opioids. Use of methadone during pregnancy is associated with neonatal abstinence syndrome (NAS), reduced head circumference as well as a slight inc...

    Authors: Francesca Tinelli, Alessandra Gamucci, Roberta Battini and Giovanni Cioni

    Citation: Italian Journal of Pediatrics 2013 39:40

    Content type: Case report

    Published on:

  48. 3-hydroxy-3-methylglutaric aciduria (OMIM 246450) is a rare autosomal recessive inborn of metabolism due to the deficiency of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase, an enzyme involved both in t...

    Authors: Francesca Santarelli, Michela Cassanello, Ausilia Enea, Francesca Poma, Valentina D'Onofrio, Giovanna Guala, Giangiacomo Garrone, Paola Puccinelli, Ubaldo Caruso, Francesco Porta and Marco Spada

    Citation: Italian Journal of Pediatrics 2013 39:33

    Content type: Case report

    Published on:

  49. Feeding small for gestational age (SGA) newborns is extremely challenging and the neonatologist should be brave and cautious at the same time. Although these babies have a high risk of milk intolerance and nec...

    Authors: Giovanni Barone, Luca Maggio, Annalisa Saracino, Alessandro Perri, Costantino Romagnoli and Enrico Zecca

    Citation: Italian Journal of Pediatrics 2013 39:28

    Content type: Review

    Published on:

  50. Intrauterine growth restriction (IUGR) and small for gestational age (SGA) birth have been considered possible indicators of the presence of malformations. The aim of this study is to evaluate such relationshi...

    Authors: Giuseppe Puccio, Mario Giuffré, Maria Piccione, Ettore Piro, Grazia Rinaudo and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2013 39:23

    Content type: Research

    Published on:

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