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Neurology, Behaviour and Development

This section considers studies on neurological, psychiatric, behavioral and developmental disorders in children and adolescents.

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  1. Content type: Case report

    Focal epilepsy with ictal abdominal pain is an unusual partial epilepsy characterized by paroxysmal episodes of abdominal or visceral pain, disturbance of awareness and electroencephalographic abnormalities. W...

    Authors: Caterina Cerminara, Nadia El Malhany, Denis Roberto and Paolo Curatolo

    Citation: Italian Journal of Pediatrics 2013 39:76

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  2. Content type: Case report

    The development of neurological complications due to varicella zoster virus (VZV) reactivation is relatively uncommon, particularly in the case of immunocompetent patients. Only a few cases have been described...

    Authors: Susanna Esposito, Samantha Bosis, Raffaella Pinzani, Laura Morlacchi, Laura Senatore and Nicola Principi

    Citation: Italian Journal of Pediatrics 2013 39:72

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  3. Content type: Case report

    Mitochondrial dysfunction manifests in many forms during childhood. There is no effective therapy for the condition; hence symptomatic therapy is the only option. The effect of symptomatic therapy are not well...

    Authors: Jun Lu and Yuanyuan Huang

    Citation: Italian Journal of Pediatrics 2013 39:60

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  4. Content type: Review

    Tuberous sclerosis complex (TSC) is a genetic multisystem disorder characterized by the development of hamartomas in several organs. Mutations in the TSC1 and TSC2 tumor suppressor genes determin overactivatio...

    Authors: Romina Moavero, Antonella Coniglio, Francesco Garaci and Paolo Curatolo

    Citation: Italian Journal of Pediatrics 2013 39:57

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  5. Content type: Research

    This review provides a synopsis for clinicians on the use of antiepileptic drugs (AEDs) in the breastfeeding mother.

    Authors: Riccardo Davanzo, Sara Dal Bo, Jenny Bua, Marco Copertino, Elisa Zanelli and Lorenza Matarazzo

    Citation: Italian Journal of Pediatrics 2013 39:50

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  6. Content type: Case report

    Prenatal ultrasonographic detection of unilateral cerebral ventriculomegaly arises suspicion of pathological condition related to cerebrospinal fluid flow obstruction or cerebral parenchimal pathology. Dyke-Da...

    Authors: Ettore Piro, Maria Piccione, Gianluca Marrone, Mario Giuffrè and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2013 39:32

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  7. Content type: Research

    Anorexia nervosa commonly arises during adolescence and is associated with more than one medical morbidity. Abnormalities in brain structure (defined as “pseudoatrophy”) are common in adolescents with anorexia...

    Authors: Monica Bomba, Anna Riva, Federica Veggo, Marco Grimaldi, Sabrina Morzenti, Francesca Neri and Renata Nacinovich

    Citation: Italian Journal of Pediatrics 2013 39:14

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  8. Content type: Case report

    Neurofibromatosis is a collective name for a group of genetic conditions in which benign tumours affect the nervous system. Type 1 is caused by a genetic mutation in the NF1 gene (OMIM 613113) and symptoms can...

    Authors: Pasquale Parisi, Severino Persechino, Maria Chiara Paolino, Francesco Nicita, Isabella Torrente, Alessandro Bozzao and Maria Pia Villa

    Citation: Italian Journal of Pediatrics 2013 39:10

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  9. Content type: Review

    Hemi-hydranencephaly is a very rare condition characterized by complete or almost near-complete unilateral absence of the cortical cortex, which is filled by a sac of cerebrospinal fluid. Prenatal vascular dis...

    Authors: Piero Pavone, Francesco Nigro, Raffaele Falsaperla, Filippo Greco, Martino Ruggieri, Renata Rizzo, Andrea D Praticò and Lorenzo Pavone

    Citation: Italian Journal of Pediatrics 2013 39:3

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  10. Content type: Research

    There is a strong need for studies evaluating tests in terms both of psychometric properties (i.e. their efficacy or ability to be helpful in reaching a diagnosis) and of their cost-effectiveness (i.e. their e...

    Authors: Matteo Chiappedi, Erika Maffioletti, Fausta Piazza, Nicole D'Adda, Marta Tamburini and Umberto Balottin

    Citation: Italian Journal of Pediatrics 2012 38:3

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  11. Content type: Research

    Attention deficit hyperactivity disorder is a behavioral syndrome of childhood characterized by inattention, hyperactivity and impulsivity. There were many etiological theories showed dysfunction of some brain...

    Authors: Magdy M Mahmoud, Abdel-Azeem M El-Mazary, Reham M Maher and Manal M Saber

    Citation: Italian Journal of Pediatrics 2011 37:60

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  12. Content type: Review

    The genetic causes underlying epilepsy remain largely unknown, and the impact of available genetic data on the nosology of epilepsy is still limited. Thus, at present, classification of epileptic disorders sho...

    Authors: Pasquale Parisi, Alberto Verrotti, Maria Chiara Paolino, Rosa Castaldo, Filomena Ianniello, Alessandro Ferretti, Francesco Chiarelli and Maria Pia Villa

    Citation: Italian Journal of Pediatrics 2011 37:58

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  13. Content type: Research

    To evaluate renal side-effects of anti-epileptic medication by valproate (VPA) and carbamazepine (CBZ), we performed a prospective study to assess renal tubular function by measuring N-acetyl-β glucosaminidase (N...

    Authors: Mojgan Mazaheri, Afshin Samaie and Vahid Semnani

    Citation: Italian Journal of Pediatrics 2011 37:21

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  14. Content type: Case report

    Neurocysticercosis represents an important cause of seizures in children in endemic countries, such as Latin America, Asia and sub-Saharan Africa, while in Europe, especially in Italy, the cases of neurocystic...

    Authors: Irene Raffaldi, Carlo Scolfaro, Federica Mignone, Sonia Aguzzi, Federica Denegri and Pier-Angelo Tovo

    Citation: Italian Journal of Pediatrics 2011 37:9

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  15. Content type: Case report

    Ischemia of the basal ganglia as an immediate consequence of minor head injury in children is rare (< 2% of all ischemic stroke in childhood) and is due to vasospasm of the lenticulostriate arteries. The clini...

    Authors: Alessandro Landi, Nicola Marotta, Cristina Mancarella, Daniele Marruzzo, Maurizio Salvati and Roberto Delfini

    Citation: Italian Journal of Pediatrics 2011 37:2

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  16. Content type: Review

    Attention-Deficit/Hyperactivity Disorder is not a single pathophysiological entity and appears to have a complex etiology. There are multiple genetic and environmental risk factors with small individual effect...

    Authors: Paolo Curatolo, Elisa D'Agati and Romina Moavero

    Citation: Italian Journal of Pediatrics 2010 36:79

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  17. Content type: Research

    Autism is a disorder of early childhood characterized by social impairment, communication abnormalities and stereotyped behaviors. The hypothalamic-pituitary-adrenocortical (HPA) axis deserves special attentio...

    Authors: Rasha T Hamza, Doaa H Hewedi and Mona A Ismail

    Citation: Italian Journal of Pediatrics 2010 36:71

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  18. Content type: Review

    Corpus callosum agenesis is a relatively common brain malformation. It can be isolated or included in a complex alteration of brain (or sometimes even whole body) morphology. It has been associated with a numb...

    Authors: Matteo Chiappedi and Maurizio Bejor

    Citation: Italian Journal of Pediatrics 2010 36:64

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  19. Content type: Case report

    Leigh syndrome is a rare progressive neurodegenerative, mitochondrial disorder of childhood with only a few cases documented from India. The clinical presentation of Leigh syndrome is highly variable. However,...

    Authors: Dhananjay Y Shrikhande, Piyush Kalakoti, MM Aarif Syed, Kunal Ahya and Gurmeet Singh

    Citation: Italian Journal of Pediatrics 2010 36:62

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  20. Content type: Letter to the Editor

    Measles Mumps Rubella (MMR) vaccination is known to cause some serious adverse events, such as fever, rash, gland inflammation and neurologic disorders. These include third and sixth cranial nerve palsies.

    Authors: Francesca Manzotti, Chiara Menozzi, Maria R Porta and Jelka G Orsoni

    Citation: Italian Journal of Pediatrics 2010 36:59

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  21. Content type: Review

    We have reviewed the literature related to the current advances in comprehension of Eating Disorders (ED) in childhood and preadolescence. The state of art regarding the psychodynamic models concerning the ons...

    Authors: Leonardo Sacrato, Alessandro Pellicciari and Emilio Franzoni

    Citation: Italian Journal of Pediatrics 2010 36:49

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  22. Content type: Research

    Knowledge and awareness about childhood autism is low among health care workers and the general populace in Nigeria. Poor knowledge about childhood autism among final year medical, nursing and psychology stude...

    Authors: Monday N Igwe, Muideen O Bakare, Ahamefule O Agomoh, Gabriel M Onyeama and Kevin O Okonkwo

    Citation: Italian Journal of Pediatrics 2010 36:44

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  23. Content type: Research

    School based mental health programs are absent in most educational institutions for intellectually disabled children and adolescents in Nigeria and co-morbid behavioral problems often complicate intellectual d...

    Authors: Muideen O Bakare, Vincent N Ubochi, Peter O Ebigbo and Andrew O Orovwigho

    Citation: Italian Journal of Pediatrics 2010 36:37

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  24. Content type: Review

    Many chromosomal abnormalities are associated with Central Nervous System (CNS) malformations and other neurological alterations, among which seizures and epilepsy. Some of these show a peculiar epileptic and ...

    Authors: Giovanni Sorge and Anna Sorge

    Citation: Italian Journal of Pediatrics 2010 36:36

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  25. Content type: Review

    Angelman syndrome (AS) is a neuro-behavioural, genetically determined condition, characterized by ataxic jerky movements, happy sociable disposition and unprovoked bouts of laughter in association with seizure...

    Authors: Agata Fiumara, Annarita Pittalà, Mariadonatella Cocuzza and Giovanni Sorge

    Citation: Italian Journal of Pediatrics 2010 36:31

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  26. Content type: Research

    In 1997 Vagus Nerve Stimulation (VNS) received approval from the US Food and Drug Administration (FDA) as an adjunctive therapy in the treatment of medically intractable partial epilepsy in people aged 12 year...

    Authors: Emilio Franzoni, Valentina Gentile, Maria Chiara Colonnelli, Daniela Brunetto, Ilaria Cecconi, Luisa Iero, Filomena C Moscano, Duccio M Cordelli and Valentina Marchiani

    Citation: Italian Journal of Pediatrics 2010 36:30

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  27. Content type: Review

    Mental retardation is a heterogeneous condition, affecting 1-3% of general population. In the last few years, several emerging clinical entities have been described, due to the advent of newest genetic techniq...

    Authors: Cinzia Galasso, Adriana Lo-Castro, Nadia El-Malhany and Paolo Curatolo

    Citation: Italian Journal of Pediatrics 2010 36:17

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  28. Content type: Letter to the Editor

    We will discuss the clinical and genetic diagnosis of a child with severe psychomotor delay, who at 3 years of age presented with paroxysms of hyperpnea-apnea and seizures unrelated to breathing anomalies.

    Authors: Grazia Taddeucci, Alice Bonuccelli, Ilaria Mantellassi, Alessandro Orsini and Enrico Tarantino

    Citation: Italian Journal of Pediatrics 2010 36:12

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  29. Content type: Research

    A number of studies have shown that current classification systems (ICD 10, DSM IV TR) have limitation when applied to autistic children and the category PDD NOS (DSM IV TR) has in particular been criticized. ...

    Authors: Matteo Chiappedi, Giorgio Rossi, Maura Rossi, Maurizio Bejor and Umberto Balottin

    Citation: Italian Journal of Pediatrics 2010 36:10

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